Optimizing macular pigments imaging in humans with visible light optical coherence tomography (OCT) and superluminescent diodes (SLD)

Alok K. Gupta; Ruoyu Meng; Vivek Srinivasan

doi:10.1117/12.3005723

13 March 2024 Optimizing macular pigments imaging in humans with visible light optical coherence tomography (OCT) and superluminescent diodes (SLD)

Alok K. Gupta, Ruoyu Meng, Vivek Srinivasan

Author Affiliations +

Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC128240D (2024) https://doi.org/10.1117/12.3005723
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Carotenoid macular pigments aid human vision and protect against advanced age-related macular degeneration (AMD). Recent work has shown that visible light Optical Coherence Tomography (OCT) can form depth-resolved images of macular pigments in the human retina. Here we compare superluminescent diodes (SLDs) at a range of center wavelengths from 452 nm to 637 nm to assess their suitability to visualize and quantify macular pigments. We consider light safety, ocular transmission (image signal-to-noise ratio), and macular pigment absorption contrast. We conclude that cyan and short wavelength green central wavelengths should provide a good balance of these competing considerations.

Conference Presentation

Citation Download Citation

Alok K. Gupta, Ruoyu Meng, and Vivek Srinivasan "Optimizing macular pigments imaging in humans with visible light optical coherence tomography (OCT) and superluminescent diodes (SLD)", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC128240D (13 March 2024); https://doi.org/10.1117/12.3005723

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