Quantification of subretinal injection volumes with intraoperative OCT using intraocular reference features

Rachel Hecht; Jacob Watson; Yuankai Tao

doi:10.1117/12.3001116

13 March 2024 Quantification of subretinal injection volumes with intraoperative OCT using intraocular reference features

Rachel Hecht, Jacob Watson, Yuankai Tao

Author Affiliations +

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC128300A (2024) https://doi.org/10.1117/12.3001116
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Real-time ophthalmic surgical decision-making benefits from volumetric visualization from intraoperative optical coherence tomography and from quantification of retinal structures during surgery. Surgeons typically rely on predetermined measurements and qualitative metrics to perform delicate operations, such as subretinal microliter volume injections for drug delivery and gene therapy. Here, we present a quantitative method for volumetric estimation of subretinal injection volume based on intraocular reference features with intraoperative optical coherence tomography for use during ophthalmic surgery. We predict this method will improve the accuracy of subretinal injections and provide better ergonomics and surgical workflow over current methods for ophthalmic surgery.

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Rachel Hecht, Jacob Watson, and Yuankai Tao "Quantification of subretinal injection volumes with intraoperative OCT using intraocular reference features", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128300A (13 March 2024); https://doi.org/10.1117/12.3001116

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KEYWORDS

Optical coherence tomography

Eye

Image segmentation

Surgery

Visualization

3D image processing

3D microstructuring

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