Double integrating sphere optical properties measurements of thermally-damaged porcine dermis

Anjelyka T. Fasci; Mark A. Keppler; Andrea L. Smith; Matthew E. Macasadia; Amanda J. Tijerina; R. Lyle Hood; Michael P. DeLisi; Joel N. Bixler

doi:10.1117/12.3000199

10 April 2024 Double integrating sphere optical properties measurements of thermally-damaged porcine dermis

Anjelyka T. Fasci, Mark A. Keppler, Andrea L. Smith, Matthew E. Macasadia, Amanda J. Tijerina, R. Lyle Hood, Michael P. DeLisi, Joel N. Bixler

Author Affiliations +

Proceedings Volume PC12840, Optical Interactions with Tissue and Cells XXXV; PC128400E (2024) https://doi.org/10.1117/12.3000199
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

High-dose laser exposure to tissue causes thermal damage and significant changes in tissue optical properties. Samples of porcine dermis and subcutaneous fat were immersed in a temperature-controlled water bath to induce a range of thermal damage. Temperature history was recorded to quantify the damage with the Arrhenius integral. Samples were then measured in a double integrating sphere setup and optical coefficients computed using the inverse adding doubling method. The tissues demonstrate non-monotonic changes in optical properties with respect to induced thermal damage. These results will inform medical scenarios and computational models where optical interaction with damaged tissues is expected.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Anjelyka T. Fasci, Mark A. Keppler, Andrea L. Smith, Matthew E. Macasadia, Amanda J. Tijerina, R. Lyle Hood, Michael P. DeLisi, and Joel N. Bixler "Double integrating sphere optical properties measurements of thermally-damaged porcine dermis", Proc. SPIE PC12840, Optical Interactions with Tissue and Cells XXXV, PC128400E (10 April 2024); https://doi.org/10.1117/12.3000199

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