Qualitative assessment of undetectable melanin distribution in lightly pigmented irides

Gladimir V.G. Baranoski; Michael W.Y. Lam

doi:10.1117/1.2747205

1 May 2007 Qualitative assessment of undetectable melanin distribution in lightly pigmented irides

Gladimir V.G. Baranoski, Michael W.Y. Lam

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Journal of Biomedical Optics, Vol. 12, Issue 3, 030501 (May 2007). https://doi.org/10.1117/1.2747205

Abstract

A longstanding issue in biomedical research concerns the biophysical factors affecting the color diversity of the human irides and its connection with ocular diseases. Although the pigmentation and morphological characteristics of heavily and moderately pigmented irides have been extensively discussed in the literature, similar studies are scarce for lightly pigmented irides. We present computer experiments indicating that the spectral signature of these specimens may be directly affected by still undetectable melanin distributions in the outermost iridal layers. Our findings represent in silico evidence of this relationship which, in turn, may have implications in the investigation of the higher risk of death from metastatic ocular melanoma verified in individuals with light-colored irides.

©(2007) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Gladimir V.G. Baranoski and Michael W.Y. Lam "Qualitative assessment of undetectable melanin distribution in lightly pigmented irides," Journal of Biomedical Optics 12(3), 030501 (1 May 2007). https://doi.org/10.1117/1.2747205

Published: 1 May 2007

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