Remittance at a single wavelength of 390  nm to quantify epidermal melanin concentration

Willem Verkruysse; Lars Othar Svaasand; Walfre Franco; J. Stuart Nelson M.D.

doi:10.1117/1.3065542

1 January 2009 Remittance at a single wavelength of 390 nm to quantify epidermal melanin concentration

Willem Verkruysse, Lars Othar Svaasand, Walfre Franco, J. Stuart Nelson M.D.

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Journal of Biomedical Optics, Vol. 14, Issue 1, 014005 (January 2009). https://doi.org/10.1117/1.3065542

Abstract

Objective quantification of epidermal melanin concentration (EMC) should be useful in laser dermatology to determine the individual maximum safe radiant exposure (IMSRE). We propose a single-wavelength remittance measurement at 390 nm as an alternative optical method to determine EMC and IMSRE. Remittance spectra (360 to 740 nm), melanin index (MI) measurements and the transient radiometric temperature increase,Δ T(t), upon skin irradiation with an Alexandrite laser (755 nm, 3-ms pulse duration, 6 J/cm²) were measured on 749 skin spots (arm and calf) on 23 volunteers (skin phototypes I to IV). Due to the shallow penetration depth and independence of blood oxygen saturation (isosbestic point), remittance at 390 nm appears to provide better estimates for EMC and IMSRE than MI.

©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Willem Verkruysse, Lars Othar Svaasand, Walfre Franco, and J. Stuart Nelson M.D. "Remittance at a single wavelength of 390 nm to quantify epidermal melanin concentration," Journal of Biomedical Optics 14(1), 014005 (1 January 2009). https://doi.org/10.1117/1.3065542

Published: 1 January 2009

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