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2 March 2012 Optical coherence photoacoustic microscopy: accomplishing optical coherence tomography and photoacoustic microscopy with a single light source
Xiangyang Zhang, Shuliang Jiao, Hao Zhang
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Journal of Biomedical Optics, Vol. 17, Issue 3, 030502 (March 2012). https://doi.org/10.1117/1.JBO.17.3.030502
Abstract
We developed optical coherence photoacoustic microscopy (OC-PAM) to demonstrate that the functions of optical coherence tomography (OCT) and photoacoustic microscopy (PAM) can be achieved simultaneously by using a single illuminating light source. We used a pulsed broadband laser centered at 580 nm and detected the absorbed photons through photoacoustic detection and the back-scattered photons with an interferometer. In OC-PAM, each laser pulse generates both one OCT A-line and one PAM A-line simultaneously; as a result, the two imaging modalities are intrinsically co-registered in the lateral directions. In vivo images of the mouse ear were acquired to demonstrate the capabilities of OC-PAM.
© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2012/$25.00 © 2012 SPIE
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Xiangyang Zhang, Shuliang Jiao, and Hao Zhang "Optical coherence photoacoustic microscopy: accomplishing optical coherence tomography and photoacoustic microscopy with a single light source," Journal of Biomedical Optics 17(3), 030502 (2 March 2012). https://doi.org/10.1117/1.JBO.17.3.030502
Published: 2 March 2012
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Cited by 47 scholarly publications and 2 patents.
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KEYWORDS
Optical coherence tomography
Light sources
Photoacoustic microscopy
Pulsed laser operation
Ultrasonics
Absorption
Near infrared
CHORUS Article. This article was made freely available starting 02 March 2013
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