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10 May 2013 Review of Monte Carlo modeling of light transport in tissues
Caigang Zhu, Quan Liu
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Journal of Biomedical Optics, Vol. 18, Issue 5, 050902 (May 2013). https://doi.org/10.1117/1.JBO.18.5.050902
Abstract
A general survey is provided on the capability of Monte Carlo (MC) modeling in tissue optics while paying special attention to the recent progress in the development of methods for speeding up MC simulations. The principles of MC modeling for the simulation of light transport in tissues, which includes the general procedure of tracking an individual photon packet, common light–tissue interactions that can be simulated, frequently used tissue models, common contact/noncontact illumination and detection setups, and the treatment of time-resolved and frequency-domain optical measurements, are briefly described to help interested readers achieve a quick start. Following that, a variety of methods for speeding up MC simulations, which includes scaling methods, perturbation methods, hybrid methods, variance reduction techniques, parallel computation, and special methods for fluorescence simulations, as well as their respective advantages and disadvantages are discussed. Then the applications of MC methods in tissue optics, laser Doppler flowmetry, photodynamic therapy, optical coherence tomography, and diffuse optical tomography are briefly surveyed. Finally, the potential directions for the future development of the MC method in tissue optics are discussed.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Caigang Zhu and Quan Liu "Review of Monte Carlo modeling of light transport in tissues," Journal of Biomedical Optics 18(5), 050902 (10 May 2013). https://doi.org/10.1117/1.JBO.18.5.050902
Published: 10 May 2013
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KEYWORDS
Tissues
Monte Carlo methods
Luminescence
Optical properties
Computer simulations
Tumor growth modeling
Scattering
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