Optimization of confocal scanning laser ophthalmoscope design

Francesco LaRocca; Al-Hafeez Dhalla; Michael P. Kelly; Sina Farsiu; Jerald A. Izatt

doi:10.1117/1.JBO.18.7.076015

17 July 2013 Optimization of confocal scanning laser ophthalmoscope design

Francesco LaRocca, Al-Hafeez Dhalla, Michael P. Kelly, Sina Farsiu, Jerald A. Izatt

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Journal of Biomedical Optics, Vol. 18, Issue 7, 076015 (July 2013). https://doi.org/10.1117/1.JBO.18.7.076015

Abstract

Confocal scanning laser ophthalmoscopy (cSLO) enables high-resolution and high-contrast imaging of the retina by employing spatial filtering for scattered light rejection. However, to obtain optimized image quality, one must design the cSLO around scanner technology limitations and minimize the effects of ocular aberrations and imaging artifacts. We describe a cSLO design methodology resulting in a simple, relatively inexpensive, and compact lens-based cSLO design optimized to balance resolution and throughput for a 20-deg field of view (FOV) with minimal imaging artifacts. We tested the imaging capabilities of our cSLO design with an experimental setup from which we obtained fast and high signal-to-noise ratio (SNR) retinal images. At lower FOVs, we were able to visualize parafoveal cone photoreceptors and nerve fiber bundles even without the use of adaptive optics. Through an experiment comparing our optimized cSLO design to a commercial cSLO system, we show that our design demonstrates a significant improvement in both image quality and resolution.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Francesco LaRocca, Al-Hafeez Dhalla, Michael P. Kelly, Sina Farsiu, and Jerald A. Izatt "Optimization of confocal scanning laser ophthalmoscope design," Journal of Biomedical Optics 18(7), 076015 (17 July 2013). https://doi.org/10.1117/1.JBO.18.7.076015

Published: 17 July 2013

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