CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12891 > Article
Presentation
13 March 2024 Compact sub-nanosecond time-gated camera based on a new 128x128 Current-Assisted Photonic Sampler (CAPS) for pre-clinical macroscale fluorescence lifetime imaging
Thomas Van den Dries, Thomas Lapauw, Simone Janssen, Sevada Sahakian, Maarten Kuijk, Hans Ingelberts
Author Affiliations +
Proceedings Volume PC12891, Silicon Photonics XIX; PC128910G (2024) https://doi.org/10.1117/12.3001047
Event: SPIE OPTO, 2024, San Francisco, California, United States
Abstract
Time-gated image sensors with (sub-) nanosecond gating times enable applications in multiple domains. Commercial Intensified CCD cameras or the more recent time-gated SPAD image sensors suffer from low Quantum Efficiency. We present an imaging system based on the tauCAM, a compact time-gated camera with our new 128x128-pixel CAPS sensor. The higher resolution is achieved with a new pixel architecture, yielding an improved fill factor. The capabilities of the new imaging system are demonstrated in a pre-clinical experimental setup. In vivo imaging in subcutaneous mice tumor models reveal that FLT imaging with the tauCAM provides additional contrast between tumor and healthy tissue, in particular for tracers sensitive to their physiological environment.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Thomas Van den Dries, Thomas Lapauw, Simone Janssen, Sevada Sahakian, Maarten Kuijk, and Hans Ingelberts "Compact sub-nanosecond time-gated camera based on a new 128x128 Current-Assisted Photonic Sampler (CAPS) for pre-clinical macroscale fluorescence lifetime imaging", Proc. SPIE PC12891, Silicon Photonics XIX, PC128910G (13 March 2024); https://doi.org/10.1117/12.3001047
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Cameras
Fluorescence lifetime imaging
Image sensors
Near infrared
Quantum sensors
Quantum efficiency
Tumors
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top