Diffuse reflectance spectroscopy study of in vitro tissue for nasopharyngeal carcinoma diagnosis

Zhihong Xu; Xueliang Lin; Xiaosong Ge; Duo Lin; Wei Huang

doi:10.1117/12.2246173

31 October 2016 Diffuse reflectance spectroscopy study of in vitro tissue for nasopharyngeal carcinoma diagnosis

Zhihong Xu, Xueliang Lin, Xiaosong Ge, Duo Lin, Wei Huang

Proceedings Volume 10024, Optics in Health Care and Biomedical Optics VII; 100243O (2016) https://doi.org/10.1117/12.2246173
Event: SPIE/COS Photonics Asia, 2016, Beijing, China

Abstract

Diffuse reflectance spectroscopy is a non-contact, non-invasive, and low-cost optical technique that provides real-time feedback about the absorptive characteristics and the microstructure properties of biological tissue. This optical technique shows the potential for monitoring metabolic status associated with malignancy transformation. Nasopharyngeal carcinoma (NPC) is the third most frequently diagnosed cancer associated with virus and is the most common male malignancy with a characteristic regional and racial distribution worldwide. This paper investigates the current screening state of nasopharyngeal malignancies and also provides an overview on the applications of diffuse reflectance spectroscopy in the cancer detection. Furthermore, the latest research relevant to the diagnosis of NPC in vitro tissue using diffuse reflectance spectroscopy is introduced. The results of diffuse reflectance spectroscopy are summarized, showing a significant experimental and clinical value for further NPC detection in vivo in the future.

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Zhihong Xu, Xueliang Lin, Xiaosong Ge, Duo Lin, and Wei Huang "Diffuse reflectance spectroscopy study of in vitro tissue for nasopharyngeal carcinoma diagnosis", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100243O (31 October 2016); https://doi.org/10.1117/12.2246173

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KEYWORDS

Diffuse reflectance spectroscopy

Tissue optics

Tissues

In vitro testing

Cancer

Absorption

Reflectivity

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