Depth-encoded dual beam phase-resolved Doppler OCT for Doppler-angle-independent flow velocity measurement

Jie Qian; Wei Cheng; Zhaoyuan Cao; Xinjian Chen; Jianhua Mo

doi:10.1117/12.2251630

17 February 2017 Depth-encoded dual beam phase-resolved Doppler OCT for Doppler-angle-independent flow velocity measurement

Jie Qian, Wei Cheng, Zhaoyuan Cao, Xinjian Chen, Jianhua Mo

Author Affiliations +

Proceedings Volume 10053, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI; 1005335 (2017) https://doi.org/10.1117/12.2251630
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Phase-resolved Doppler optical coherence tomography (PR-D-OCT) is a functional OCT imaging technique that can provide high-speed and high-resolution depth-resolved measurement on flow in biological materials. However, a common problem with conventional PR-D-OCT is that this technique often measures the flow motion projected onto the OCT beam path. In other words, it needs the projection angle to extract the absolute velocity from PR-D-OCT measurement. In this paper, we proposed a novel dual-beam PR-D-OCT method to measure absolute flow velocity without separate measurement on the projection angle. Two parallel light beams are created in sample arm and focused into the sample at two different incident angles. The images produced by these two beams are encoded to different depths in single B-scan. Then the Doppler signals picked up by the two beams together with the incident angle difference can be used to calculate the absolute velocity. We validated our approach in vitro on an artificial flow phantom with our home-built 1060 nm swept source OCT. Experimental results demonstrated that our method can provide an accurate measurement of absolute flow velocity with independency on the projection angle.

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Jie Qian, Wei Cheng, Zhaoyuan Cao, Xinjian Chen, and Jianhua Mo "Depth-encoded dual beam phase-resolved Doppler OCT for Doppler-angle-independent flow velocity measurement", Proc. SPIE 10053, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI, 1005335 (17 February 2017); https://doi.org/10.1117/12.2251630

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KEYWORDS

Velocity measurements

Optical coherence tomography

Doppler tomography

Doppler effect

In vitro testing

Capillaries

Motion measurement

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