Terahertz spectra of drug-laden magnetic nanoparticles

Olga A. Smolyanskaya; Valery N. Trukhin; Polina G. Gavrilova; Evgeniy L. Odlyanitskiy; Anna V. Semenova; Quentin Cassar; Jean-Paul Guillet; Patrick Mounaix; Kamil G. Gareev; Dmitry V. Korolev

doi:10.1117/12.2506870

7 March 2019 Terahertz spectra of drug-laden magnetic nanoparticles

Olga A. Smolyanskaya, Valery N. Trukhin, Polina G. Gavrilova, Evgeniy L. Odlyanitskiy, Anna V. Semenova, Quentin Cassar, Jean-Paul Guillet, Patrick Mounaix, Kamil G. Gareev, Dmitry V. Korolev

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Proceedings Volume 10892, Colloidal Nanoparticles for Biomedical Applications XIV; 108920L (2019) https://doi.org/10.1117/12.2506870
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Drag-laden magnetic nanoparticles can deliver drugs to a zone of ischemic damage for various purposes of clinical medicine. THz spectroscopy of nanoparticles with adsorbed organic and biological molecules could enable estimation of drug delivery efficiency of the nanoparticles sample and curative effect of delivering chemical substance. The first task of this work was to simulate the contribution of nanoparticles and the shell of organic molecules (glycose) to the dielectric properties of the pressed pellets, consisting of the polyethylene and nanoparticles. The second task of this paper was to study experimentally the possibility of using terahertz radiation for spectral diagnosis of NPs based on iron oxide in a biologically inert shell of silicon dioxide drug-laden with a glycose.

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Olga A. Smolyanskaya, Valery N. Trukhin, Polina G. Gavrilova, Evgeniy L. Odlyanitskiy, Anna V. Semenova, Quentin Cassar, Jean-Paul Guillet, Patrick Mounaix, Kamil G. Gareev, and Dmitry V. Korolev "Terahertz spectra of drug-laden magnetic nanoparticles", Proc. SPIE 10892, Colloidal Nanoparticles for Biomedical Applications XIV, 108920L (7 March 2019); https://doi.org/10.1117/12.2506870

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