Sensitivity in differential phase contrast - limits and strategies to improve it

Chiara Bonati; Timothé Laforest; Mathieu Kunzi; Christophe Moser

doi:10.1117/12.2579760

5 March 2021 Sensitivity in differential phase contrast - limits and strategies to improve it

Chiara Bonati, Timothé Laforest, Mathieu Kunzi, Christophe Moser

Proceedings Volume 11653, Quantitative Phase Imaging VII; 116530Q (2021) https://doi.org/10.1117/12.2579760
Event: SPIE BiOS, 2021, Online Only

Abstract

The phase sensitivity limit of Differential Phase Contrast (DPC) with partially coherent light is analyzed in details. The main optical parameters, such as the shape of illumination and the numerical aperture of the objective, together with the noise of the camera used to determine the minimum phase that can be detected. We found that a priori information about the sample can be used to fine-tune these parameters to increase phase contrast. We propose a simple algorithm to predict phase sensitivity of a DPC setup, which can be performed before the setup is built. Experiments confirm the theoretical findings.

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Citation Download Citation

Chiara Bonati, Timothé Laforest, Mathieu Kunzi, and Christophe Moser "Sensitivity in differential phase contrast - limits and strategies to improve it", Proc. SPIE 11653, Quantitative Phase Imaging VII, 116530Q (5 March 2021); https://doi.org/10.1117/12.2579760

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