Multi-configuration Raman spectrometer for early stage diagnosis of oral cancer

Siddra Maryam; Marcelo Saito Nogueira; Shree Krishna Moorthy; Sanathana Sekar; Huihui Lu; Rekha Gautam; Ray Burke; Stefan Andersson-Engels; Richeal Ni Riordain; Patrick Sheahan

doi:10.1117/12.2610704

2 March 2022 Multi-configuration Raman spectrometer for early stage diagnosis of oral cancer

Siddra Maryam, Marcelo Saito Nogueira, Shree Krishna Moorthy, Sanathana Sekar, Huihui Lu, Rekha Gautam, Ray Burke, Stefan Andersson-Engels, Richeal Ni Riordain, Patrick Sheahan

Author Affiliations +

Proceedings Volume 11957, Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry; 1195706 (2022) https://doi.org/10.1117/12.2610704
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

The Oral Squamous Cell carcinoma (OSCC) is one of the most common and aggressive oral malignancies. Despite all significant advances in medicine, five-year survival rate is still low. This study aims to develop a full scheme for diagnosing oral cancer in early stages by using Raman spectroscopy. Patients undergoing biopsy or histopathological examination will be enrolled in this study. Ex vivo measurement will be carried out using saliva specimens and in vivo analysis will involve measurements taken on healthy and malignant tissue. In the future, this optical diagnostic approach using Raman spectroscopy and SERS can help in improving diagnostic accuracy and the survival rate by affecting the treatment outcome via early stage detection of oral cancer.

Conference Presentation

Citation Download Citation

Siddra Maryam, Marcelo Saito Nogueira, Shree Krishna Moorthy, Sanathana Sekar, Huihui Lu, Rekha Gautam, Ray Burke, Stefan Andersson-Engels, Richeal Ni Riordain, and Patrick Sheahan "Multi-configuration Raman spectrometer for early stage diagnosis of oral cancer", Proc. SPIE 11957, Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry, 1195706 (2 March 2022); https://doi.org/10.1117/12.2610704

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available