Transcranial imaging with the optoacoustic memory effect

Xosé Luís Deán-Ben; Daniel Razansky

doi:10.1117/12.2608160

3 March 2022 Transcranial imaging with the optoacoustic memory effect

Xosé Luís Deán-Ben, Daniel Razansky

Proceedings Volume 11960, Photons Plus Ultrasound: Imaging and Sensing 2022; 119600M (2022) https://doi.org/10.1117/12.2608160
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Severe distortion of ultrasound waves traversing the skull impedes visualization of cerebral structures in humans. Accurate modelling of ultrasound propagation effects is challenging due to highly heterogeneous acoustic properties of the skull bone. Here we demonstrate that acoustic distortions induced by the skull are preserved for optoacoustic waves generated at neighboring point sources. This memory effect is exploited for building a model describing generation and detection of a signal originating from light-absorbing particle at given position. Model-based inversion is shown to accurately recover the absorption distribution with comparable spatial resolution to that obtained without the presence of the skull.

Citation Download Citation

Xosé Luís Deán-Ben and Daniel Razansky "Transcranial imaging with the optoacoustic memory effect", Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119600M (3 March 2022); https://doi.org/10.1117/12.2608160

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