Temporal evolution of optical properties at different temperatures of biological tissues

Alessandro Bossi; Leonardo Bianchi; Paola Saccomandi; Antonio Giovanni Pifferi

doi:10.1117/12.2649110

7 March 2023 Temporal evolution of optical properties at different temperatures of biological tissues

Alessandro Bossi, Leonardo Bianchi, Paola Saccomandi, Antonio Giovanni Pifferi

Author Affiliations +

Proceedings Volume 12376, Optical Tomography and Spectroscopy of Tissue XV; 123760M (2023) https://doi.org/10.1117/12.2649110
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Thermal therapy is a minimally invasive technique with great potential for treating tumors in non-surgical candidates. Minimally invasive procedures reduce post-operation complications and improve patient quality of life.¹ Thermal therapies work by inducing damage to a tissue using heat. There are several types of Thermal therapies, such as microwave ablation, laser ablation, or radiofrequency ablation. The current limitation is the treatment control² to limit the damage to healthy tissue and treat the cancerous regions entirely. The search for an effective tool for monitoring the thermal outcome is still ongoing. Diffuse optics could monitor during and after the thermal therapy as the optical properties are linked to the damage level³⁴ received by the tissue. In this work, we aimed to study the change in the optical properties of a porcine muscle during a thermal treatment to identify the reactions that occur during the therapy to study their evolution.

Conference Presentation

Citation Download Citation

Alessandro Bossi, Leonardo Bianchi, Paola Saccomandi, and Antonio Giovanni Pifferi "Temporal evolution of optical properties at different temperatures of biological tissues", Proc. SPIE 12376, Optical Tomography and Spectroscopy of Tissue XV, 123760M (7 March 2023); https://doi.org/10.1117/12.2649110

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