Full-view low-cost LED-based optoacoustic tomography

Xiang Liu; Sandeep Kumar Kalva; Berkan Lafci; Daniil Nozdriukhin; Xosé Luís Deán-Ben; Daniel Razansky

doi:10.1117/12.3000380

12 March 2024 Full-view low-cost LED-based optoacoustic tomography

Xiang Liu, Sandeep Kumar Kalva, Berkan Lafci, Daniil Nozdriukhin, Xosé Luís Deán-Ben, Daniel Razansky

Proceedings Volume 12842, Photons Plus Ultrasound: Imaging and Sensing 2024; 128420G (2024) https://doi.org/10.1117/12.3000380
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Optoacoustic tomography is typically implemented with bulky solid-state lasers delivering per-pulse energies in the millijoule range. Light emitting diodes (LEDs) represent a cost-effective and portable alternative for signal excitation further offering excellent pulse-to-pulse stability. Herein, we describe a full-view LED-based optoacoustic tomography (FLOAT) system for deep-tissue in vivo imaging. A custom-made electronic unit driving a stacked array of LEDs attains stable light pulses with total per-pulse energy of 0.48 mJ and 100 ns pulse width. The LED array was arranged on a circular configuration and integrated in a full-ring ultrasound array enabling full-view tomographic imaging performance in cross-sectional (2D) geometry. As a proof of concept, we scanned the medial phalanx of the index finger without extrinsic administration of a contrast agent. We anticipate that this compact, affordable, and versatile illumination technology will facilitate dissemination of the optoacoustic technology in resource-limited settings.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Xiang Liu, Sandeep Kumar Kalva, Berkan Lafci, Daniil Nozdriukhin, Xosé Luís Deán-Ben, and Daniel Razansky "Full-view low-cost LED-based optoacoustic tomography", Proc. SPIE 12842, Photons Plus Ultrasound: Imaging and Sensing 2024, 128420G (12 March 2024); https://doi.org/10.1117/12.3000380

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