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17 June 2002 Laser soldering of pig skin in vivo using IR fiber optic temperature control system
David Simhon M.D., Avi Ravid, Marissa Halpern M.D., Tamar Brosh, T. Vasilyev, Daniel Levanon, Noam Kariv, Abraham Katzir
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Proceedings Volume 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII; (2002) https://doi.org/10.1117/12.433862
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States
Abstract
Background and objectives: A feedback temperature controlled laser soldering system was used for bonding cut wounds on the skins of young and mature pigs. This is a step towards clinical implantation of this promising novel technique. Materials and methods: 47% bovine serum albumin (BSA) solder was applied onto cuts created in dorsally d epilated skin on the backs of pigs, weighing 8 -10Kg or 74Kg. A temperature fiberoptic CO2 laser system was used to monitor and control the temperature of a spot on the cut at a desired temperature. For given values of time and temperature, a 28 days follow up of the soldered scars was obtained and compared with standard suturing. Results: Optimal soldering temperature was found to be 65ºC. The tensile strength of laser-soldered cuts was measured after 3-28 days postoperatively and was found similar to that of sutured cuts. Macroscopic and microscopic studies showed better and faster wound healing of soldered scars compared with standard sutures. All soldered scars in the mature pig, demonstrated excellent healing with no signs of dehiscence. Conclusions: Temperature controlled laser soldering of cut wounds in pig skin offers several advantages over standard suturing techniques. This novel method should be tested clinically.
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David Simhon M.D., Avi Ravid, Marissa Halpern M.D., Tamar Brosh, T. Vasilyev, Daniel Levanon, Noam Kariv, and Abraham Katzir "Laser soldering of pig skin in vivo using IR fiber optic temperature control system", Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); https://doi.org/10.1117/12.433862
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KEYWORDS
Laser welding
Skin
Gas lasers
Control systems
Tissues
Optical fibers
Carbon monoxide
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