Mueller matrix optical imaging with application to tissue diagnostics

Ajaina A. Nezhuvingal; Yanfang Li; Harini Anumula; Brent D. Cameron

doi:10.1117/12.477688

27 August 2003 Mueller matrix optical imaging with application to tissue diagnostics

Ajaina A. Nezhuvingal, Yanfang Li, Harini Anumula, Brent D. Cameron

Proceedings Volume 4961, Laser-Tissue Interaction XIV; (2003) https://doi.org/10.1117/12.477688
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

In this paper we present experimental results demonstrating processing techniques developed in our laboratory that can be utilized to decode or extract useful information from two-dimensional Mueller matrices of turbid media. Through the use of these methods, involving the partial least squares technique, it is shown how scattering coefficient contributions as a function of particle size can be estimated for a given sample. Furthermore, we demonstrate how a spatial selection algorithm known as "chain select" can be used to help facilitate the interpretation of the measured Mueller matrix images. The samples utilized in this investigation were comprised of polystyrene spheres with diameters ranging from 200 nm to 2000 nm and analyzed with 514 nm light. At this wavelength, both Rayleigh and Mie-types of scattering are observed.

Citation Download Citation

Ajaina A. Nezhuvingal, Yanfang Li, Harini Anumula, and Brent D. Cameron "Mueller matrix optical imaging with application to tissue diagnostics", Proc. SPIE 4961, Laser-Tissue Interaction XIV, (27 August 2003); https://doi.org/10.1117/12.477688

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