Creating the invisible man

A. J. Welch; Chris Humphrey; Gracie Vargas; Oliver F. Stumpp; Chris G. Rylander

doi:10.1117/12.537256

1 July 2004 Creating the invisible man

A. J. Welch, Chris Humphrey, Gracie Vargas, Oliver F. Stumpp, Chris G. Rylander

Proceedings Volume 5319, Laser Interaction with Tissue and Cells XV; (2004) https://doi.org/10.1117/12.537256
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm²] required to coagulate dermal blood vessels.

Citation Download Citation

A. J. Welch, Chris Humphrey, Gracie Vargas, Oliver F. Stumpp, and Chris G. Rylander "Creating the invisible man", Proc. SPIE 5319, Laser Interaction with Tissue and Cells XV, (1 July 2004); https://doi.org/10.1117/12.537256

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