Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications

Georgi Borislawow Graschew; Matthias Bastian; Stefan Rakowsky; Theo A. Roelofs; Evangelos Balanos; Peter M. Schlag

doi:10.1117/12.579510

23 December 2004 Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications

Georgi Borislawow Graschew, Matthias Bastian, Stefan Rakowsky, Theo A. Roelofs, Evangelos Balanos, Peter M. Schlag

Author Affiliations +

Proceedings Volume 5620, Solid State Laser Technologies and Femtosecond Phenomena; (2004) https://doi.org/10.1117/12.579510
Event: European Symposium on Optics and Photonics for Defence and Security, 2004, London, United Kingdom

Abstract

Multiphoton excitation of selected dye molecules for laser-induced fluorescence diagnosis (LIFD) and optical biopsy of biological tissue and microbiological samples has various advantages: greater tissue penetration, more spatial resolution and less photo-bleaching. New applicators and microscopical set-ups for the delivery of the fs-pulsed laser radiation as required for multiphoton LIFD and optical biopsy need to be developed. Beam delivery solutions and workplaces for microbiological and tissue diagnosis are presented.

Citation Download Citation

Georgi Borislawow Graschew, Matthias Bastian, Stefan Rakowsky, Theo A. Roelofs, Evangelos Balanos, and Peter M. Schlag "Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications", Proc. SPIE 5620, Solid State Laser Technologies and Femtosecond Phenomena, (23 December 2004); https://doi.org/10.1117/12.579510

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