The development of a real-time monitoring and auto-controlling PDT system

Jiumin Yang; Yingxin Li M.D.; Tiegen Liu; Yu Zhao

doi:10.1117/12.807510

13 October 2008 The development of a real-time monitoring and auto-controlling PDT system

Jiumin Yang, Yingxin Li M.D., Tiegen Liu, Yu Zhao

Proceedings Volume 7129, Seventh International Symposium on Instrumentation and Control Technology: Optoelectronic Technology and Instruments, Control Theory and Automation, and Space Exploration; 71291S (2008) https://doi.org/10.1117/12.807510
Event: Seventh International Symposium on Instrumentation and Control Technology, 2008, Beijing, China

Abstract

Measurement of concentration of photosensitizer, tissue oxygen can reveal information about tissue metabolism and effects of photodynamic therapy (PDT). The purpose of this study is to develop a monitoring and auto-controlling laser system for PDT instrument. The concentration of issue oxygen is detected by near-infrared spectroscopy (NIRS). The blood drug level of photosensitizer is monitored during PDT by fluorescence spectroscopy which was induced by 532 nm Laser. The Laser's output power and idle time can be determined by those monitored parameters. Thus, this system will provide insights into ways to enhance treatment's effectiveness and selectivity in clinical operation.

Citation Download Citation

Jiumin Yang, Yingxin Li M.D., Tiegen Liu, and Yu Zhao "The development of a real-time monitoring and auto-controlling PDT system", Proc. SPIE 7129, Seventh International Symposium on Instrumentation and Control Technology: Optoelectronic Technology and Instruments, Control Theory and Automation, and Space Exploration, 71291S (13 October 2008); https://doi.org/10.1117/12.807510

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