Analysis of the spectrum in phase-contrast mammography

Adam M. Zysk; Qiaofeng Xu; Luis de Sisternes; Jovan G. Brankov; Miles N. Wernick; Mark A. Anastasio

doi:10.1117/12.812146

13 March 2009 Analysis of the spectrum in phase-contrast mammography

Adam M. Zysk, Qiaofeng Xu, Luis de Sisternes, Jovan G. Brankov, Miles N. Wernick, Mark A. Anastasio

Proceedings Volume 7258, Medical Imaging 2009: Physics of Medical Imaging; 72584E (2009) https://doi.org/10.1117/12.812146
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

It has been proposed that the sensitivity of breast lesion detection can be improved with phase-contrast mammographic imaging. The recently introduced clinical system by Konica-Minolta, for example, reportedly yields enhanced lesion detectability. We hypothesize that the use of an optimized x-ray spectrum will result in even better performance. To test this hypothesis, we have performed a study of several clinical spectra from Mo and W sources over a broad spectral range. In the study, we have incorporated established dose measurements from a simple breast phantom used in the digital mammography literature, which has been updated to incorporate breast density properties in addition to conventional attenuation information. Established phase-contrast imaging simulation techniques, which employed a Fresnel propagator, were used to generate edge-enhanced radiographs for analysis. In addition, detector sensitivity and tube loading parameters were incorporated into the analysis. The resulting mammography images were analyzed via measurement of object edge-enhanced contrast.

Citation Download Citation

Adam M. Zysk, Qiaofeng Xu, Luis de Sisternes, Jovan G. Brankov, Miles N. Wernick, and Mark A. Anastasio "Analysis of the spectrum in phase-contrast mammography", Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72584E (13 March 2009); https://doi.org/10.1117/12.812146

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