Ultrahigh-speed ultrahigh-resolution adaptive optics: optical coherence tomography system for in-vivo small animal retinal imaging

Yifan Jian; Jing Xu; Robert J. Zawadzki; Marinko V. Sarunic

doi:10.1117/12.2006652

20 March 2013 Ultrahigh-speed ultrahigh-resolution adaptive optics: optical coherence tomography system for in-vivo small animal retinal imaging

Yifan Jian, Jing Xu, Robert J. Zawadzki, Marinko V. Sarunic

Author Affiliations +

Proceedings Volume 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII; 85711R (2013) https://doi.org/10.1117/12.2006652
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Small animal models of human retinal diseases are a critical component of vision research. In this report, we present an ultrahigh-resolution ultrahigh-speed adaptive optics optical coherence tomography (AO-OCT) system for small animal retinal imaging (mouse, fish, etc.). We adapted our imaging system to different types of small animals in accordance with the optical properties of their eyes. Results of AO-OCT images of small animal retinas acquired with AO correction are presented. Cellular structures including nerve fiber bundles, capillary networks and detailed double-cone photoreceptors are visualized.

Citation Download Citation

Yifan Jian, Jing Xu, Robert J. Zawadzki, and Marinko V. Sarunic "Ultrahigh-speed ultrahigh-resolution adaptive optics: optical coherence tomography system for in-vivo small animal retinal imaging", Proc. SPIE 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, 85711R (20 March 2013); https://doi.org/10.1117/12.2006652

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