Coherent spectroscopic techniques applied to molecular sensing at the nanoscale

Alexei V. Sokolov; Volker Deckert; Zhenhuan Yi; Marlan O. Scully

doi:10.1117/12.2616778

9 March 2022 Coherent spectroscopic techniques applied to molecular sensing at the nanoscale

Alexei V. Sokolov, Volker Deckert, Zhenhuan Yi, Marlan O. Scully

Proceedings Volume PC12016, Optical and Quantum Sensing and Precision Metrology II; PC120161D (2022) https://doi.org/10.1117/12.2616778
Event: SPIE OPTO, 2022, San Francisco, California, United States

Abstract

We report on our progress toward an ultrasensitive Raman-spectroscopic tool for nano-scale probing and imaging of biological objects such as viruses and cells. Our approach is based on laser spectroscopy aided by plasmonic nanoantennas, as in tip-enhanced Raman spectroscopy (TERS). An additional enhancement in sensitivity and speed can be obtained by employing the femtosecond adaptive spectroscopic technique (FAST) for coherent anti-Stokes Raman scattering (CARS). The combined approach will enable nondestructive label-free biosensing with molecular-level sensitivity and with spatial resolution down to a fraction of a nanometer.

Conference Presentation

Citation Download Citation

Alexei V. Sokolov, Volker Deckert, Zhenhuan Yi, and Marlan O. Scully "Coherent spectroscopic techniques applied to molecular sensing at the nanoscale", Proc. SPIE PC12016, Optical and Quantum Sensing and Precision Metrology II, PC120161D (9 March 2022); https://doi.org/10.1117/12.2616778

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