1060-nm compact SECM system with tethered endoscopic capsule for esophageal imaging in vivo.

Junyoung Kim; Edward C. Farewell; Sung-Bin J. Yun; Abhishek Srinivas; Paola Leon Alarcon; Sydney R. Kutowy; Abigail L. Gregg; Guillermo Tearney

doi:10.1117/12.2652331

17 March 2023 1060-nm compact SECM system with tethered endoscopic capsule for esophageal imaging in vivo.

Junyoung Kim, Edward C. Farewell, Sung-Bin J. Yun, Abhishek Srinivas, Paola Leon Alarcon, Sydney R. Kutowy, Abigail L. Gregg, Guillermo Tearney

Author Affiliations +

Proceedings Volume PC12356, Endoscopic Microscopy XVIII; PC123560K (2023) https://doi.org/10.1117/12.2652331
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We present the compact SECM system with a 3D-printed tethered endoscopic capsule with a 1060 nm center wavelength. Compared to the previously presented 1310 nm SECM system, the present SECM system theoretically provides 15% improved lateral resolution, 5.2 times faster imaging speed, and two times faster fabrication times. We performed in vivo imaging on the swine esophagus and the SECM images clearly visualized squamous cell nuclei as a bright dot surrounded by dark cytoplasm and bright cell borders. These results indicate that our new SECM endoscopic system making it easier to conduct cellular-level diagnosis of upper GI tract.

Conference Presentation

Citation Download Citation

Junyoung Kim, Edward C. Farewell, Sung-Bin J. Yun, Abhishek Srinivas, Paola Leon Alarcon, Sydney R. Kutowy, Abigail L. Gregg, and Guillermo Tearney "1060-nm compact SECM system with tethered endoscopic capsule for esophageal imaging in vivo.", Proc. SPIE PC12356, Endoscopic Microscopy XVIII, PC123560K (17 March 2023); https://doi.org/10.1117/12.2652331

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