Liver resection surgery in a swine model using indocyanine green and a novel near-infrared fluorescent dye (BL-760)

Sailee Naik; Aneesh Naik; Christy Lee; Yoseph Kim; Jaepyeong Cha; So-Hyun Nam M.D.; Michele Saruwatari

doi:10.1117/12.2650938

6 March 2023 Liver resection surgery in a swine model using indocyanine green and a novel near-infrared fluorescent dye (BL-760)

Sailee Naik, Aneesh Naik, Christy Lee, Yoseph Kim, Jaepyeong Cha, So-Hyun Nam M.D., Michele Saruwatari

Author Affiliations +

Proceedings Volume PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI; PC1236806 (2023) https://doi.org/10.1117/12.2650938
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Many liver resection surgeries are performed with fluorescence-guided approaches using near-infrared (NIR) fluorescent dyes, such as indocyanine green (ICG), in an effort to prevent postoperative bile leakage. However, these existing fluorophores have limitations when assessing bile leakages and other bile duct injuries. We have reported a novel NIR fluorescent dye, BL-760, that we believe would be favorable over ICG and other NIR dyes during hepatectomies. We will describe our hepatic resection surgery study conducted with a swine model while comparing the advantages and disadvantages of common fluorescent dyes and the novel BL-760 dye.

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Citation Download Citation

Sailee Naik, Aneesh Naik, Christy Lee, Yoseph Kim, Jaepyeong Cha, So-Hyun Nam M.D., and Michele Saruwatari "Liver resection surgery in a swine model using indocyanine green and a novel near-infrared fluorescent dye (BL-760)", Proc. SPIE PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI, PC1236806 (6 March 2023); https://doi.org/10.1117/12.2650938

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