Rigid stable real-time OCT en face registration for intrasurgical optical coherence tomography

Philipp Matten; Michael Sommersperger; Shervini Dehghani; Meriç Feyzullahoğlu; Jonas Nienhaus; Wolfgang Drexler; Rainer A. Leitgeb; Tilman Schmoll; Nassir Navab

doi:10.1117/12.3000902

13 March 2024 Rigid stable real-time OCT en face registration for intrasurgical optical coherence tomography

Philipp Matten, Michael Sommersperger, Shervini Dehghani, Meriç Feyzullahoğlu, Jonas Nienhaus, Wolfgang Drexler, Rainer A. Leitgeb, Tilman Schmoll, Nassir Navab

Author Affiliations +

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC1283009 (2024) https://doi.org/10.1117/12.3000902
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

4D microscope-integrated optical coherence tomography has emerged as a valuable tool for ophthalmic surgery. However, it is still not clear how to make the best, computationally efficient use of the abundant data generated. Many techniques require accurate registration of successive volume streams. To address this need, we present a real-time machine learning method for lateral registration based on en face projections. Our proposed network predicts the lateral translational and rotational offset, which can be corrected. As ground truth, we use homography matrices from the displacements of en face images. Our pipeline thus allows for real-time, rigid registration of en face maps derived from sequentially acquired volumes, and is able to accurately correct for lateral distortions at a volume rate of 20 Hz. We therefore believe that this method could enable real-time rigid volume registration for 4D microscopy integrated optical coherence tomography.

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Citation Download Citation

Philipp Matten, Michael Sommersperger, Shervini Dehghani, Meriç Feyzullahoğlu, Jonas Nienhaus, Wolfgang Drexler, Rainer A. Leitgeb, Tilman Schmoll, and Nassir Navab "Rigid stable real-time OCT en face registration for intrasurgical optical coherence tomography", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283009 (13 March 2024); https://doi.org/10.1117/12.3000902

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KEYWORDS

Optical coherence tomography

Image registration

Education and training

Surgery

Biomedical applications

Computer simulations

Decision making

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