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13 March 2024 3D fluorescence molecular tomography utilizing a novel SPAD camera
Navid Ibtehaj Nizam, Vikas Pandey, Ismail Erbas, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Xavier Michalet, Xavier Intes
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Proceedings Volume PC12834, Multimodal Biomedical Imaging XIX; PC1283407 (2024) https://doi.org/10.1117/12.2692977
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
3D Fluorescence Molecular Tomography (FMT) is an important pre-clinical tool for quantifying and characterizing molecular markers for different diseases. Herein, we demonstrate, for the first time, 3D K-Space FMT reconstructions using a large time-gated SPAD camera, SwissSPAD2 (SS2). The 3D reconstruction results are obtained using traditional and Deep Neural Network-based inverse solvers. Moreover, the 3D reconstruction performance with SS2 is benchmarked against that obtained with a gated-ICCD camera. The reconstruction results obtained using SS2 are in good agreement with those obtained from the gated-ICCD.
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(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.
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Navid Ibtehaj Nizam, Vikas Pandey, Ismail Erbas, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Xavier Michalet, and Xavier Intes "3D fluorescence molecular tomography utilizing a novel SPAD camera", Proc. SPIE PC12834, Multimodal Biomedical Imaging XIX, PC1283407 (13 March 2024); https://doi.org/10.1117/12.2692977
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KEYWORDS
Cameras
Fluorescence
Fluorescence tomography
Imaging systems
Stereoscopic cameras
Fluorescence imaging
Near infrared
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