Determination of the optical properties of anisotropic biological media using an isotropic diffusion model

Alwin Kienle; Corinna Wetzel; Andrea Li Bassi; Daniela Comelli; Paola Taroni; Antonio Pifferi

doi:10.1117/1.2709864

1 January 2007 Determination of the optical properties of anisotropic biological media using an isotropic diffusion model

Alwin Kienle, Corinna Wetzel, Andrea Li Bassi, Daniela Comelli, Paola Taroni, Antonio Pifferi

Author Affiliations +

Journal of Biomedical Optics, Vol. 12, Issue 1, 014026 (January 2007). https://doi.org/10.1117/1.2709864

Abstract

We investigate anisotropic light propagation in biological tissue in steady-state and time domains. Monte Carlo simulations performed for tissue that consists of aligned cylindrical and spherical scatterers show that steady-state and time-resolved reflectance depends strongly on the measurement direction relative to the alignment of the cylinder axis. We examine the determination of optical properties using an isotropic diffusion model and find that in the time domain, in contrast to steady-state spatially resolved reflectance measurements, the obtained absorption coefficient does not depend on the measurement direction and is close to the true value. Contrarily, the derived reduced scattering coefficient depends strongly on the measurement direction in both domains. Measurements of the steady-state and time-resolved reflectance from bovine tendon confirm the theoretical findings.

©(2007) Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation Download Citation

Alwin Kienle, Corinna Wetzel, Andrea Li Bassi, Daniela Comelli, Paola Taroni, and Antonio Pifferi "Determination of the optical properties of anisotropic biological media using an isotropic diffusion model," Journal of Biomedical Optics 12(1), 014026 (1 January 2007). https://doi.org/10.1117/1.2709864

Published: 1 January 2007

ACCESS THE FULL ARTICLE

JOURNAL ARTICLE
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

CITATIONS

Cited by 41 scholarly publications.

Explore citations on Lens.org

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Monte Carlo methods

Reflectivity

Scattering

Optical properties

Diffusion

Optical fibers

Absorption

Show All Keywords

RELATED CONTENT

Reliable determination of tissue optical properties from spatially resolved reflectance
Proceedings of SPIE (March 14 2017)

Finite element simulation of light transfer in turbid media under...
Proceedings of SPIE (May 01 2017)

A comparison of isotropic and anisotropic diffuse models in determining...
Proceedings of SPIE (February 09 2012)

Influence of the phase function on the determination of the...
Proceedings of SPIE (October 31 2001)

Superficial tissue optical property determination using spatially resolved measurements close...
Proceedings of SPIE (July 15 1999)

Determination of the optical properties of anisotropic biological media using...
Proceedings of SPIE (July 12 2007)

An inverse Monte-Carlo method for determining tissue optical properties
Proceedings of SPIE (February 13 2007)

Subscribe to Digital Library

Receive Erratum Email Alert

Show All Keywords

Keywords/Phrases

Search In:

Publication Years