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9 November 2016 Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler
Robin Guay-Lord, Xavier Attendu, Kristen L. Lurie, Lucas Majeau, Nicolas Godbout, Audrey K. Bowden, Mathias Strupler, Caroline Boudoux
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Journal of Biomedical Optics, Vol. 21, Issue 11, 116008 (November 2016). https://doi.org/10.1117/1.JBO.21.11.116008
Abstract
This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information contained in the hyperspectral image. The HSI data can be used to highlight the presence of specific molecules with characteristic absorption peaks or to produce true color images overlaid on the OCT volume for improved tissue identification by the clinician. Such a system could be implemented in a number of clinical endoscopic applications and could improve the current practice in tissue characterization, diagnosis, and surgical guidance.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Robin Guay-Lord, Xavier Attendu, Kristen L. Lurie, Lucas Majeau, Nicolas Godbout, Audrey K. Bowden, Mathias Strupler, and Caroline Boudoux "Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler," Journal of Biomedical Optics 21(11), 116008 (9 November 2016). https://doi.org/10.1117/1.JBO.21.11.116008
Published: 9 November 2016
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Cited by 21 scholarly publications and 3 patents.
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KEYWORDS
Optical coherence tomography
Hyperspectral imaging
Absorption
Fiber couplers
Tissues
Cladding
Reflectivity
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