A multipurpose integrated preclinical device that combines Blood-Brain Barrier permeabilization, Photo-Thermal Therapy (PTT) with photoacoustic thermometry, was developed as a novel preclinical versatile research instrument for the development of new PTT for Glioblastoma multiforme.
In situ temperature monitoring with photoacoustic measurements is introduced in an integrated setup, specifically designed for photothermotherapy treatmentof the glioblastoma, aided by nanoparticles and HIFU blood-brain barrier opening.
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