Mr. Carlos Yeh Profile

Carlos Yeh

at National Chiao Tung Univ

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Proceedings Article | 29 April 2005 Paper

Identify the centerline of tubular structure in medical images

Yu-Tai Ching, Carlos Yeh

Proceedings Volume 5747, (2005) https://doi.org/10.1117/12.595318

KEYWORDS: Neurons, Image segmentation, Angiography, Confocal microscopy, Medical imaging, 3D image processing, Arteries, Shape analysis, Detection and tracking algorithms, Model-based design

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Finding the centerline of the tubular structure helps to segment or analyze the organs such as the vessels or neuron fibers in medical images. This paper described a semi-automatic method using the minimum cost path finding and Hessian matrix analysis in scale space to calculate the centerline of tubular structure organs. Unlike previous approaches, exhaustive search for line-like shapes in every scale is prevent. Centerline pixels candidates and the width of the vessel are extracted by analyzing the intensity profile along the gradient vectors in the image. A verification procedure using Hassian matrix analysis with the scale obtained from the gradient analysis is applied to those candidates. Results obtained from the Hessian matrix analysis are used to construct a weighted graph. Finding the minimum cost path in the graph gives the centerline of the tubular structure. The method is applied to find the centerline of the vessels in the 2D angiogram and the neuron fibers in the 3D confocal microscopic images.

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