Mr. Gaurav Jayswal Profile

Gaurav Jayswal

Post-Doc at King Abdullah Univ of Science and Technology

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 20 June 2024 Presentation + Paper

Ultra-trace detection of biomarker employing Au gratings as highly sensitive SERS-active substrate

Sibashish Chakraborty, Richa Goel, Vimarsh Awasthi, Gaurav Jayaswal, Satish Dubey

Proceedings Volume 12999, 129991M (2024) https://doi.org/10.1117/12.3022333

KEYWORDS: Surface enhanced Raman spectroscopy, Raman spectroscopy, Urea, Electron beam lithography, Molecules, Gold, Metals, Silicon, Reproducibility, Plasmonics

Read Abstract +

Surface Enhanced Raman Spectroscopy, also known as SERS, is a technology that has developed into an effective, rapid, accurate, and sensitive method for the detection and analysis of any analyte at the ultra-trace level. This is accomplished by the enhancement of the Raman signal. The SERS technique allows for the identification of very low quantities of Raman-active analytes by coupling electromagnetic radiation at optical frequency. There is a substantial amount of interest in the study of the design and development of SERS-active substrates due to the fact that these substrates are of crucial importance in the process of Raman signal amplification. In this study, we have demonstrated EBL fabricated, Au-gratings nanopattern as SERS-active substrate for detection of Rhodamine 6G and a bio-molecule urea up to 10^-9 M concentration. NIR laser source (λ=785nm) was used to collect Raman spectra using Raman set up (Renishaw). As part of normal bodily functions, the liver releases urea into the blood, which is transported to the kidneys and expelled as urine, serving as a biomarker for kidney disease. Gas chromatography and calorimetry can detect low quantities of urea, but they are time-consuming and costly. As a low-cross-section molecule, urea can be adsorbed on noble-metal NPs and detected at trace amounts using SERS. There are a number of other possible applications for the SERS-active substrate that has been presented. These applications include in-situ detection of food and water adulterants, narco-analysis etc.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years