Dr. Vanesa Lukinsone Profile

Dr. Vanesa Lukinsone

Leading researcher at Univ. of Latvia

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Publications (16)

SPIE Journal Paper | 21 February 2022 Open Access

Skin chromophore mapping by smartphone RGB camera under spectral band and spectral line illumination

Ilona Kuzmina, Ilze Oshina, Laura Dambite, Vanesa Lukinsone, Anna Maslobojeva, Anna Berzina, Janis Spigulis

JBO, Vol. 27, Issue 02, 026004, (February 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.2.026004

KEYWORDS: Skin, Light emitting diodes, Prototyping, Chromophores, RGB color model, Cameras, Photons, Fiber optic illuminators, Image processing, Diagnostics

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Significance: Multispectral imaging enables mapping of chromophore content changes in skin neoplasms, which helps to diagnose a pathology. Different types of light sources can be used for the imaging. Design of laser-based illuminators is more complicated and, consequently, they are more expensive than LED-based illuminators. On the other hand, spectral line illumination has the advantage of less complicated calculations, since only the discrete maximum wavelengths need to be considered. Spectral band and spectral line approaches for multispectral skin diagnostics have not been compared so far. This can help to evaluate the accuracy and effectiveness of both approaches. Aim: To compare two specific illumination modalities—spectral band and spectral line illumination—from the point of performance for mapping of in vivo skin chromophores. Approach: Three spectral images of the same skin malformations were captured by a smartphone RGB camera with two different add-on illuminators comprising LED emitters and laser emitters, respectively. Five types of benign skin neoplasms were included in our study. Concentrations of skin melanin, oxy- and deoxy-hemoglobin at image pixel groups were calculated using the Beer–Lambert law. Results: Skin chromophore maps and statistical analysis of mean concentrations’ changes in the neoplasms compared to the surrounding skin are presented and discussed. The data of the laser emitters led to significantly higher (∼10 times) increase of the oxy-hemoglobin values in vascular neoplasms and much lower deoxy-hemoglobin values, if compared to the data obtained by the LED emitters. Conclusions: Analysis of the obtained chromophore distribution maps and concentration variations in neoplasms led to conclusion that the spectral line illumination approach is more appropriate for this application. Considering only the peak wavelengths of illumination spectral bands leads to essentially different results if compared to those obtained by spectral line illumination and may cause misinterpretations in the clinical assessment of skin neoplasms.

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Proceedings Article | 28 October 2020 Paper

Biophotonics research in Riga: recent projects and results

Janis Spigulis, Ilona Kuzmina, Ilze Lihacova, Vanesa Lukinsone, Blaž Cugmas, Andris Grabovskis, Edgars Kviesis-Kipge, Alexey Lihachev

Proceedings Volume 11585, 1158502 (2020) https://doi.org/10.1117/12.2581799

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Proceedings Article | 20 August 2020 Presentation

Skin chromophore mapping from multi-spectral laser line images

Ilze Ošina, Ilona Kuzmina, Uldis Rubins, Vanesa Lukinsone, Anna Maslobojeva, Laura Dambite, Margarita Matulenko, Zigmars Rupenheits, Janis Spigulis

Proceedings Volume 11483, 114830A (2020) https://doi.org/10.1117/12.2568069

KEYWORDS: Skin, Chromophores, In vivo imaging, Diagnostics, Cancer, Skin cancer, Prototyping, Tissue optics, Light scattering, Wound healing

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Proceedings Article | 2 April 2020 Presentation + Paper

Remitted photon path length in human skin, skin phantoms and cell cultures

V. Lukinsone, I. Kuzmina, M. Tamosiunas, A. Maslobojeva, M. Kuzminskis, U. Rubins, J. Spigulis

Proceedings Volume 11363, 1136320 (2020) https://doi.org/10.1117/12.2555822

KEYWORDS: Skin, Tissues, Photon transport, Chromophores, Picosecond phenomena, Light scattering, Time correlated photon counting

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Proceedings Article | 2 April 2020 Presentation + Paper

Agar-based phantoms for skin diagnostic imaging

Ilona Kuzmina, Vanesa Lukinsone, Uldis Rubins, Ilze Osina, Laura Dambite, Anna Maslobojeva, Janis Spigulis

Proceedings Volume 11363, 113630F (2020) https://doi.org/10.1117/12.2555674

KEYWORDS: RGB color model, Skin, Prototyping, Absorption, Diffuse reflectance spectroscopy, Chromophores, Transmittance, Light emitting diodes, Optical properties, Scattering

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Proceedings Article | 17 February 2020 Paper

Towards combined multispectral, FLIM and Raman imaging for skin diagnostics

J. Spigulis, I. Kuzmina, V. Lukinsone, M. Tamošiūnas, I. Oshina, L. Ozolina, A. Maslobojeva, M. Kuzminskis, D. Ivanov, E. Borisova

Proceedings Volume 11232, 112320N (2020) https://doi.org/10.1117/12.2559107

KEYWORDS: Raman spectroscopy, Skin, Diagnostics, Multispectral imaging, Luminescence, Prototyping, Fluorescence lifetime imaging, Light emitting diodes, Cameras, RGB color model

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Proceedings Article | 22 July 2019 Paper

Towards direct measurements of remitted photon path lengths in skin: kinetic studies in the range 520-800 nm

V. Lukinsone, M. Osis, J. Latvels, I. Kuzmina, U. Rubins, N. Zorina, A. Maslobojeva, J. Spigulis

Proceedings Volume 11075, 1107505 (2019) https://doi.org/10.1117/12.2526663

KEYWORDS: Skin, Signal detection, Picosecond phenomena, Absorption, Tissues, Chromophores, Neodymium, Scattering, Data processing, Tissue optics

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Proceedings Article | 3 June 2019 Paper

Multispectral and autofluorescence RGB imaging for skin cancer diagnostics

V. Lukinsone, I. Kuzmina, R. Veilande, E. V. Plorina, D. Bliznuks, K. Bolochko, A. Derjabo, I. Lihacova, J. Spigulis

Proceedings Volume 11065, 110650A (2019) https://doi.org/10.1117/12.2518882

KEYWORDS: Skin, Melanoma, Diagnostics, Multispectral imaging, Diffuse reflectance spectroscopy, Light emitting diodes, RGB color model, Skin cancer, Image processing, Cameras

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Proceedings Article | 29 January 2019 Paper

Lasers for in-vivo skin diagnostics: some recent developments

Janis Spigulis, Alexey Lihachev, Vanesa Lukinsone, Martins Osis , Ilze Oshina

Proceedings Volume 11047, 1104703 (2019) https://doi.org/10.1117/12.2516747

KEYWORDS: Skin, Chromophores, Diagnostics, RGB color model, In vivo imaging, Picosecond phenomena, Luminescence, Image filtering, Cameras, Tumors

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SPIE Journal Paper | 14 September 2017 Open Access

FRET-based method for evaluation of the efficiency of reversible and irreversible sonoporation

Paulius Ruzgys, Mindaugas Tamošiūnas, Vanesa Lukinsone, Saulius Šatkauskas

JBO, Vol. 22, Issue 09, 097001, (September 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.9.097001

KEYWORDS: Luminescence, Absorption, Fluorescence resonance energy transfer, Molecules, Proteins, Pollution control, Microscopy, Image processing, Resonance energy transfer, Molecular energy transfer

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SPIE Journal Paper | 11 December 2015 Open Access

Autofluorescence imaging of basal cell carcinoma by smartphone RGB camera

Alexey Lihachev, Alexander Derjabo, Inesa Ferulova, Marta Lange, Ilze Lihacova, Janis Spigulis

JBO, Vol. 20, Issue 12, 120502, (December 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.120502

KEYWORDS: Atrial fibrillation, Skin, Tumors, RGB color model, Tissues, Image filtering, Cameras, Auto-fluorescence imaging, Optical filters, Luminescence

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Proceedings Article | 6 May 2015 Paper

Simultaneous detection of tissue autofluorescence decay distribution and time-gated photo-bleaching rates

Alexey Lihachev, Inesa Ferulova, Janis Spigulis, Mindaugas Tamosiunas

Proceedings Volume 9504, 95040P (2015) https://doi.org/10.1117/12.2178827

KEYWORDS: Atrial fibrillation, Skin, Tissue optics, Tissues, Photon counting, In vivo imaging, Luminescence, Time correlated photon counting, Fluorescence spectroscopy, Single photon

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SPIE Journal Paper | 30 January 2015 Open Access

Photobleaching effects on in vivo skin autofluorescence lifetime

Inesa Ferulova, Alexey Lihachev, Janis Spigulis

JBO, Vol. 20, Issue 05, 051031, (January 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.051031

KEYWORDS: Skin, In vivo imaging, Luminescence, Continuous wave operation, Absorption, Picosecond phenomena, Laser irradiation, Molecular interactions, Molecular lasers, Pulsed laser operation

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Proceedings Article | 18 November 2013 Paper

Fluorescence spectroscopy for estimation of anticancer drug sonodestruction in vitro

A. Lihachev, D. Jakovels, I. Ferulova, J. Spigulis, M. Tamosiunas, S. Satkauskas, C. Lo, W. Chen

Proceedings Volume 9032, 90320D (2013) https://doi.org/10.1117/12.2044658

KEYWORDS: Luminescence, Ultrasonography, Fluorescence spectroscopy, Spectroscopy, In vitro testing, Fiber optics tests, Fiber optics, Oxygen, Acoustic cavitation, Molecules

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Proceedings Article | 18 November 2013 Paper

Fluorescence lifetime spectroscopy: potential for in-vivo estimation of skin fluorophores changes after low power laser treatment

Inesa Ferulova, Alexey Lihachev, Janis Spigulis

Proceedings Volume 9032, 90320B (2013) https://doi.org/10.1117/12.2044688

KEYWORDS: Skin, Luminescence, In vivo imaging, Continuous wave operation, Tissue optics, Fluorescence spectroscopy, Spectroscopy, Laser therapeutics, Laser irradiation, Diffuse reflectance spectroscopy

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Proceedings Article | 8 May 2012 Paper

Influence of low power CW laser irradiation on skin hemoglobin changes

Inesa Ferulova, Janis Lesins, Alexey Lihachev, Dainis Jakovels, Janis Spigulis

Proceedings Volume 8427, 84273I (2012) https://doi.org/10.1117/12.922601

KEYWORDS: Skin, Laser irradiation, Absorbance, Continuous wave operation, Diffuse reflectance spectroscopy, Absorption, Multispectral imaging, Spectroscopy, Cameras, Tissue optics

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Showing 5 of 16 publications

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