Dr. Mark F. Coughlan Profile

Dr. Mark F. Coughlan

Instructor in Medicine at Harvard University

SPIE Involvement:

Author

Area of Expertise:

Biophotonics , Microscopy , Spectroscopy , Integrated Photonics

Websites:

Company Website

Publications (5)

Proceedings Article | 12 March 2024 Presentation + Paper

Endoscopic light scattering spectroscopy for in vivo detection of pre-cancer in bile duct

Le Qiu, Douglas Pleskow, Mandeep Sawhney, Paul Upputuri, Tyler Berzin, Mark Coughlan, Umar Khan, Xuejun Zhang, Jonah Cohen, Yuri Zakharov, Lei Zhang, Lev Perelman

Proceedings Volume 12856, 1285603 (2024) https://doi.org/10.1117/12.2692402

KEYWORDS: Cancer detection, Diagnostics, Scattering, In vivo imaging, Backscatter, Tissues, Spectroscopy, Light scattering, Endoscopy, Cancer

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Proceedings Article | 9 August 2023 Paper

C-CLASS microscopy allows the detection of nanoscale changes in chromatin structure

Mark Coughlan, Giuseppe Pettinato, Maria Glyavina, Xuejun Zhang, Liming Chen, Umar Khan, Paul Upputuri, Yuri Zakharov, Lei Zhang, Le Qiu, Lev Perelman

Proceedings Volume 12630, 126300U (2023) https://doi.org/10.1117/12.2667044

KEYWORDS: Light scattering, Spectroscopy, Confocal microscopy, Imaging spectroscopy

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Proceedings Article | 3 March 2022 Paper

A portable light scattering system for detecting expelled droplets to assess Covid-19 transmission risk

Mark Coughlan, Mandeep Sawhney, Douglas Pleskow, Tyler Berzin, Umar Khan, Maria Glyavina, Xuejun Zhang, Liming Chen, Paul Upputuri, Conor Sheil, Mohammad Bilal, Joseph Feuerstein, Andy Silva-Santisteban, Yuri Zakharov, Edward Vitkin, Irving Itzkan, Lei Zhang, Le Qiu, Lev Perelman

Proceedings Volume 11974, 1197406 (2022) https://doi.org/10.1117/12.2608902

KEYWORDS: Scattering, Light scattering, Particles, Cameras, Visualization, Sensors, Imaging systems, Endoscopy, Computer aided design, Aerosols

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Proceedings Article | 3 March 2022 Presentation

Spectroscopic label-free light scattering microscopy of chromatin organization and dynamics in live cells

Mark Coughlan, Maria Glyavina, Giuseppe Pettinato, Yuri Zakharov, Xuejun Zhang, Umar Khan, Liming Chen, Paul Upputuri, Edward Vitkin, Irving Itzkan, Lei Zhang, Le Qiu, Lev Perelman

Proceedings Volume PC11974, PC1197408 (2022) https://doi.org/10.1117/12.2608948

KEYWORDS: Light scattering, Spectroscopy, Microscopy, Confocal microscopy, Genomics, Diffraction, Structural dynamics, Scattering, Natural surfaces, Nanotechnology

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Proceedings Article | 5 March 2021 Presentation

Imaging and spectroscopy with scattered light from the tissue to chromatin scale

Mark Coughlan, Maria Glyavina, Xuejun Zhang, Umar Khan, Yuri Zakharov, Edward Vitkin, Lei Zhang, Irving Itzkan, Douglas Pleskow, Le Qiu, Lev Perelman

Proceedings Volume 11622, 116220D (2021) https://doi.org/10.1117/12.2590876

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