Prof. Michelle Digman Profile

Prof. Michelle Digman

at Univ of California Irvine

SPIE Involvement:

Conference Program Committee | Author

Proceedings Article | 13 March 2024 Presentation

FLIM reveals bioenergetic shifts in Alzheimer’s disease and aging

Michelle Digman

Proceedings Volume PC12847, PC128470E (2024) https://doi.org/10.1117/12.3026595

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Proceedings Article | 13 March 2024 Presentation

Advancing optical metabolic imaging through phasor-based S-FLIM-SHG microscopy

Belen Torrado, Alexander Vallmitjana, Michelle Digman, Alexander Dvornikov, Enrico Gratton

Proceedings Volume PC12847, PC128470R (2024) https://doi.org/10.1117/12.3009991

KEYWORDS: Optical imaging, Microscopy, Second harmonic generation, Microscopes, Fluorescence lifetime imaging, Ultraviolet radiation, Photons, Photobleaching, Multiphoton fluorescence microscopy, Molecules

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Proceedings Article | 13 March 2024 Open Access

Single-cell organelle phenotyping

Michelle Digman

Proceedings Volume PC12836, PC1283601 (2024) https://doi.org/10.1117/12.3029539

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Proceedings Article | 13 March 2024 Presentation

Multimodal imaging techniques to investigate metabolic signatures, lipid droplets, and collagen remodeling in breast cancer spheroids

Michelle Digman, Giulia Tedeschi, Francesco Palomba, Lorenzo Scipioni

Proceedings Volume PC12833, PC128330G (2024) https://doi.org/10.1117/12.3009135

KEYWORDS: Collagen, Breast cancer, Multimodal imaging, Tumors, Signal processing, Matrices, Fluorescence lifetime imaging, Breast, Spectroscopy, Solids

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Proceedings Article | 15 March 2023 Open Access

The Phasor approach to FLIM: Metabolic imaging reveals how P53 and REV3L regulate energy metabolism in lung carcinoma cells (Conference Presentation)

Michelle Digman

Proceedings Volume PC12384, PC1238402 (2023) https://doi.org/10.1117/12.2653032

KEYWORDS: Fluorescence lifetime imaging, Lung, Mode conditioning cables, Lung cancer, Cancer, Resistance, Cell death, Proteins, Polymers, Oncology

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Proceedings Article | 2 March 2022 Presentation

Metabolic imaging using the phasor approach to FLIM and tracking phenotypic change of mitochondria in cancer cells with Mitometer

Michelle Digman

Proceedings Volume PC11967, PC1196705 (2022) https://doi.org/10.1117/12.2619390

KEYWORDS: Fluorescence lifetime imaging, Cancer, Tumors, Breast cancer, Motion measurement, Image segmentation, Detection and tracking algorithms, Breast, Algorithm development, Resistance

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SPIE Journal Paper | 29 June 2018 Open Access

Feasibility study on mouse live imaging after spinal cord injury and poly(lactide-co-glycolide) bridge implantation

Andrea Anzalone, Jenu Chacko, Rebecca Nishi, Courtney Dumont, Dominique Smith, Lonnie Shea, Michelle Digman, Brian Cummings, Aileen Anderson

JBO, Vol. 23, Issue 06, 065007, (June 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.6.065007

KEYWORDS: Bridges, Spinal cord, Optical fibers, Injuries, Signal detection, Molecular bridges, Luminescence, Visualization, Axons, Microscopes

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Proceedings Article | 13 February 2009 Open Access

Multicolor fluctuation spectroscopy in cells

Michelle Digman, Enrico Gratton

Proceedings Volume 7183, 718303 (2009) https://doi.org/10.1117/12.814875

KEYWORDS: Fluorescence correlation spectroscopy, Diffusion, Proteins, Molecules, Particles, Microscopes, Luminescence, Spectroscopy, Data analysis, Molecular spectroscopy

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