Dr. Molly Brewer Profile

Dr. Molly Brewer

at University of Connecticut

SPIE Involvement:

Author

Publications (31)

SPIE Journal Paper | 18 April 2016 Open Access

Coregistered photoacoustic and ultrasound imaging and classification of ovarian cancer: ex vivo and in vivo studies

Hassan Salehi, Hai Li, Alex Merkulov, Patrick Kumavor, Hamed Vavadi, Melinda Sanders, Angela Kueck, Molly Brewer, Quing Zhu

JBO, Vol. 21, Issue 04, 046006, (April 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.4.046006

KEYWORDS: Acquisition tracking and pointing, Ovary, In vivo imaging, Ovarian cancer, Photoacoustic spectroscopy, Ultrasonography, Tissues, Spatial filters, Feature extraction, Imaging systems

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SPIE Journal Paper | 28 January 2016 Open Access

Characterizing optical properties and spatial heterogeneity of human ovarian tissue using spatial frequency domain imaging

Sreyankar Nandy, Atahar Mostafa, Patrick Kumavor, Melinda Sanders, Molly Brewer, Quing Zhu

JBO, Vol. 21, Issue 10, 101402, (January 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.10.101402

KEYWORDS: Absorption, Scattering, Tissues, Ovary, Tissue optics, Optical properties, Imaging systems, Radon transform, Tumor growth modeling, Ovarian cancer

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Proceedings Article | 11 March 2015 Paper

Wavelength optimization for in vivo multispectral photoacoustic/ultrasound tomography of hemoglobin oxygenation in ovarian cancer: clinical studies

Hassan Salehi, Hai Li, Patrick Kumavor, Aleksey Merkulov, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 9323, 932303 (2015) https://doi.org/10.1117/12.2080385

KEYWORDS: In vivo imaging, Oxygen, Photoacoustic spectroscopy, Ovarian cancer, Tumors, Ovary, Ultrasonography, Imaging systems, Acquisition tracking and pointing, Tomography

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Proceedings Article | 6 March 2015 Paper

Estimation of elastic parameters of ovarian tissue using phase stabilized swept source optical-coherence tomography

Sreyankar Nandy, Tianheng Wang, Hassan Salehi, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 9327, 93270D (2015) https://doi.org/10.1117/12.2080202

KEYWORDS: Tissues, Tissue optics, Optical coherence tomography, Ovary, Elastography, Transducers, Optical tomography, Tomography, Coherence (optics), Collagen

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SPIE Journal Paper | 11 September 2014 Open Access

Texture analysis applied to second harmonic generation image data for ovarian cancer classification

Bruce Wen, Molly Brewer, Oleg Nadiarnykh, James Hocker, Vikas Singh, Thomas Mackie, Paul Campagnola

JBO, Vol. 19, Issue 09, 096007, (September 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.9.096007

KEYWORDS: Tissues, Ovarian cancer, Image classification, Second-harmonic generation, Cancer, Collagen, Harmonic generation, Image filtering, Tumor growth modeling, Biological research

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Proceedings Article | 3 March 2014 Paper

Quantification of photoacoustic microscopy images for ovarian cancer detection

Tianheng Wang, Yi Yang, Umar Alqasemi, Patrick Kumavor, Xiaohong Wang, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 8943, 894306 (2014) https://doi.org/10.1117/12.2036129

KEYWORDS: Ovary, Tissues, Tumor growth modeling, Radon transform, Photoacoustic microscopy, Ovarian cancer, Feature extraction, Photoacoustic spectroscopy, Ultrasonography, Transducers

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Proceedings Article | 20 March 2013 Paper

Characterization of ovarian tissue using polarization-sensitive optical coherence tomography

Tianheng Wang, Yi Yang, Xiaohong Wang, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 8571, 857124 (2013) https://doi.org/10.1117/12.2001515

KEYWORDS: Ovary, Tissue optics, Scattering, Optical coherence tomography, Tissues, Ovarian cancer, Polarization, Quantitative analysis, Cancer, Collagen

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Proceedings Article | 20 March 2013 Paper

Measurement of angle-resolved scattering property of ovarian tissue by use of OCT

Yi Yang, Tianheng Wang, Molly Brewer, Quing Zhu

Proceedings Volume 8571, 85711Q (2013) https://doi.org/10.1117/12.2006848

KEYWORDS: Ovary, Scattering, Optical coherence tomography, Collagen, Tissues, Tissue optics, Scatter measurement, Coherence imaging, Natural surfaces, Tumor growth modeling

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Proceedings Article | 4 March 2013 Paper

Photoacoustic microscopy for ovarian tissue characterization

Tianheng Wang, Yi Yang, Umar Alqasemi, Patrick Kumavor, Molly Brewer, Quing Zhu

Proceedings Volume 8581, 85814M (2013) https://doi.org/10.1117/12.2007725

KEYWORDS: Ovary, Tissues, Tissue optics, Radon transform, Photoacoustic spectroscopy, Transducers, Ultrasonography, Photoacoustic microscopy, Error analysis, Feature extraction

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SPIE Journal Paper | 6 September 2012 Open Access

Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography

Yi Yang, Tianheng Wang, Quing Zhu, Molly Brewer

JBO, Vol. 17, Issue 9, 090503, (September 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.9.090503

KEYWORDS: Ovary, Scattering, Optical coherence tomography, Collagen, Tissue optics, Tissues, Quantitative analysis, Light scattering, Biological research, Coherence imaging

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SPIE Journal Paper | 4 July 2012 Open Access

Analysis of second-harmonic-generation microscopy in a mouse model of ovarian carcinoma

Jennifer Watson, Photini Rice, Urs Utzinger, Jennifer Barton, Samuel Marion, Patricia Hoyer, Molly Brewer, John Davis, Jeffrey Rodríguez

JBO, Vol. 17, Issue 7, 076002, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.076002

KEYWORDS: Ovary, Collagen, Ovarian cancer, Cancer, Diagnostics, Second-harmonic generation, Tumors, Image analysis, Microscopy, Optical fibers

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Proceedings Article | 1 February 2012 Paper

An intraoperative probe combining positron detection and OCT imaging for ovarian cancer detection and characterization

Yi Yang, Tianheng Wang, Nrusingh Biswal, Patrick Kumavor, Xiaohong Wang, Mozafareddin Karimeddini, John Vento, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 8220, 82200E (2012) https://doi.org/10.1117/12.907023

KEYWORDS: Optical coherence tomography, Ovary, Ovarian cancer, Tissues, Scattering, Sensors, Tissue optics, Cancer, Positron emission tomography, Computed tomography

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Proceedings Article | 1 February 2012 Paper

Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images

Yi Yang, Tianheng Wang, Nrusingh Biswal, Xiaohong Wang, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 8213, 82130C (2012) https://doi.org/10.1117/12.909535

KEYWORDS: Scattering, Optical coherence tomography, Tissue optics, Collagen, Ovary, Tissues, Ovarian cancer, Signal attenuation, Tumor growth modeling, Statistical analysis

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SPIE Journal Paper | 1 September 2011 Open Access

Optical scattering coefficient estimated by optical coherence tomography correlates with collagen content in ovarian tissue

Yi Yang, Tianheng Wang, Nrusingh Biswal, Molly Brewer, Quing Zhu, Xiaohong Wang, Melinda Sanders

JBO, Vol. 16, Issue 09, 090504, (September 2011) https://doi.org/10.1117/12.10.1117/1.3625247

KEYWORDS: Tissues, Collagen, Optical coherence tomography, Scattering, Tissue optics, Ovary, Ovarian cancer, Tumor growth modeling, Natural surfaces, Optical testing

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Proceedings Article | 22 February 2011 Paper

Multi-modality optical imaging of ovarian cancer in a post-menopausal mouse model

Jennifer Watson, Photini Faith Rice, Samuel Marion, David Bentley, Molly Brewer, Urs Utzinger, Patricia Hoyer, Jennifer Barton

Proceedings Volume 7890, 78900W (2011) https://doi.org/10.1117/12.875577

KEYWORDS: Ovary, Optical coherence tomography, Ovarian cancer, Tissues, In vivo imaging, Optical imaging, Second-harmonic generation, Cancer, Microscopes, Mouse models

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Proceedings Article | 18 February 2011 Paper

Toward in-vivo photoacoustic imaging of human ovarian tissue for cancer detection

Andres Aguirre, Patrick Kumavor, Yasaman Ardeshirpour, Mary Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 7899, 789908 (2011) https://doi.org/10.1117/12.875950

KEYWORDS: Ovary, Ultrasonography, Ovarian cancer, Photoacoustic spectroscopy, Transducers, Photoacoustic imaging, In vivo imaging, Cancer, Vagina, Absorption

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Proceedings Article | 10 February 2011 Paper

A hybrid positron and OCT intraoperative probe for ovarian cancer detection and characterization

Yi Yang, Nrusingh Biswal, Tianheng Wang, Patrick Kumavor, Mozafareddin Karimeddini, Melinda Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 7892, 78920Y (2011) https://doi.org/10.1117/12.878860

KEYWORDS: Optical coherence tomography, Ovary, Ovarian cancer, Sensors, Tissues, Cancer, Image resolution, Tumors, Diagnostics, Multimodal imaging

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SPIE Journal Paper | 1 September 2010 Open Access

Clinical research device for ovarian cancer detection by optical spectroscopy in the ultraviolet C-visible

Ronie George, Archana Chandrasekaran, Molly Brewer, Kenneth Hatch, Urs Utzinger

JBO, Vol. 15, Issue 05, 057009, (September 2010) https://doi.org/10.1117/12.10.1117/1.3503468

KEYWORDS: Fiber optics, Luminescence, Calibration, Ovarian cancer, Optical filters, Ovary, Spectroscopy, Tissue optics, Light sources, Optical spectroscopy

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Proceedings Article | 24 February 2010 Paper

Photoacoustic characterization of human ovarian tissue

Andres Aguirre, Yasaman Ardeshirpour, Mary Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 7564, 75643G (2010) https://doi.org/10.1117/12.845828

KEYWORDS: Ovary, Ultrasonography, Photoacoustic spectroscopy, Ovarian cancer, Absorption, Photoacoustic imaging, Imaging systems, Cancer, Tissue optics, Transducers

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SPIE Journal Paper | 1 September 2009 Open Access

Coregistered three-dimensional ultrasound and photoacoustic imaging system for ovarian tissue characterization

Andres Aguirre, Puyun Guo, John Gamelin, Shikui Yan, Mary Sanders, Molly Brewer, Quing Zhu

JBO, Vol. 14, Issue 05, 054014, (September 2009) https://doi.org/10.1117/12.10.1117/1.3233916

KEYWORDS: Ultrasonography, Photoacoustic spectroscopy, Ovary, Imaging systems, Photoacoustic imaging, Transducers, Tissue optics, Ovarian cancer, 3D image processing, Cancer

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Proceedings Article | 25 February 2009 Paper

Photoacoustic characterization of ovarian tissue

Andres Aguirre, John Gamelin, Puyun Guo, Shikui Yan, Mary Sanders, Molly Brewer, Quing Zhu

Proceedings Volume 7177, 717708 (2009) https://doi.org/10.1117/12.812754

KEYWORDS: Ultrasonography, Photoacoustic spectroscopy, Ovary, Tissue optics, Cancer, Ovarian cancer, Photoacoustic imaging, Absorption, Imaging systems, Transducers

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Proceedings Article | 23 February 2009 Paper

Laparoscopic optical coherence tomographic imaging of human ovarian cancer

Lida Hariri, Garret Bonnema, Kathy Schmidt, Vrushali Korde, Amy Winkler, Kenneth Hatch, Molly Brewer, Jennifer Barton

Proceedings Volume 7169, 71690S (2009) https://doi.org/10.1117/12.809167

KEYWORDS: Optical coherence tomography, Ovary, Laparoscopy, Ovarian cancer, Tissues, Glasses, Coherence imaging, Coherence (optics), Collagen, Visualization

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SPIE Journal Paper | 1 March 2008 Open Access

Computer-aided identification of ovarian cancer in confocal microendoscope images

Saurabh Srivastava, Jeffrey Rodríguez, Andrew Rouse, Molly Brewer, Arthur Gmitro

JBO, Vol. 13, Issue 02, 024021, (March 2008) https://doi.org/10.1117/12.10.1117/1.2907167

KEYWORDS: Confocal microscopy, Tissues, Ovarian cancer, Feature selection, Error analysis, Natural surfaces, Statistical analysis, Principal component analysis, Pathology, Ovary

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Proceedings Article | 21 February 2008 Paper

Laparoscopic optical coherence tomographic imaging of human ovarian cancer

Lida Hariri, Garret Bonnema, Kathy Schmidt, Kenneth Hatch, Molly Brewer, Jennifer Barton

Proceedings Volume 6851, 685107 (2008) https://doi.org/10.1117/12.760995

KEYWORDS: Optical coherence tomography, Laparoscopy, Ovary, Ovarian cancer, Coherence imaging, Tissues, Collagen, Coherence (optics), Image resolution, In vivo imaging

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Proceedings Article | 12 February 2007 Paper

Confocal microendoscope for use in a clinical setting

Joshua Udovich, Andrew Rouse, Anthony Tanbakuchi, Molly Brewer, Richard Sampliner, Arthur Gmitro

Proceedings Volume 6432, 64320H (2007) https://doi.org/10.1117/12.701798

KEYWORDS: Confocal microscopy, Imaging systems, Tissues, In vivo imaging, Adaptive optics, Objectives, Ovary, Control systems, Safety, Mirrors

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SPIE Journal Paper | 1 July 2006 Open Access

Dual modality imaging of a novel rat model of ovarian carcinogenesis

Elizabeth Kanter, Ross Walker, Sam Marion, Molly Brewer, Patricia Hoyer, Jennifer Barton

JBO, Vol. 11, Issue 04, 041123, (July 2006) https://doi.org/10.1117/12.10.1117/1.2236298

KEYWORDS: Ovary, Optical coherence tomography, Laser induced fluorescence, Ovarian cancer, Cancer, Luminescence, Control systems, Tumor growth modeling, Tissues, Animal model studies

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Proceedings Article | 8 October 2005 Paper

Multiphoton imaging of an in vitro ovarian tissue model

Nathaniel Kirkpatrick, Molly Brewer, Urs Utzinger

Proceedings Volume 5860, 586002 (2005) https://doi.org/10.1117/12.632938

KEYWORDS: Tissues, Ovary, Luminescence, In vitro testing, Biopsy, Imaging systems, Collagen, Tissue optics, Natural surfaces, Spectroscopy

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Proceedings Article | 29 March 2005 Paper

Intrinsic fluorescence biomarkers in cells treated with chemopreventive drugs

Nathaniel Kirkpatrick, William Brands, Changping Zou, Molly Brewer, Urs Utzinger

Proceedings Volume 5699, (2005) https://doi.org/10.1117/12.591363

KEYWORDS: Luminescence, Cancer, Fluorescence spectroscopy, Bladder, Bladder cancer, Ovary, Cell death, Statistical analysis, Ovarian cancer, Oncology

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Proceedings Article | 24 March 2005 Paper

Automated texture-based identification of ovarian cancer in confocal microendoscope images

Saurabh Srivastava, Jeffrey Rodriguez, Andrew Rouse, Molly Brewer, Arthur Gmitro

Proceedings Volume 5701, (2005) https://doi.org/10.1117/12.590592

KEYWORDS: Confocal microscopy, Tissues, Ovarian cancer, Feature selection, Biopsy, Ovary, Statistical analysis, Principal component analysis, Cancer, Error analysis

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Proceedings Article | 7 March 2005 Paper

Endogenous fluorescence emission of the ovary

Urs Utzinger, Nathaniel Kirkpatrick, Rebekah Drezek, Molly Brewer

Proceedings Volume 5702, (2005) https://doi.org/10.1117/12.591378

KEYWORDS: Ovarian cancer, Cancer, Luminescence, Ovary, Biopsy, Ultraviolet radiation, Tissues, Tissue optics, Principal component analysis, Fluorescence spectroscopy

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SPIE Journal Paper | 1 January 2002 Open Access

Fluorescence spectroscopy as a biomarker in a cell culture and in a nonhuman primate model for ovarian cancer chemopreventive agents

Molly Brewer, Urs Utzinger, Yang Li, Edward Atkinson, William Satterfield, Nelly Auersperg, Rebecca Richards-Kortum, Michele Follen, Robert Bast

JBO, Vol. 7, Issue 01, (January 2002) https://doi.org/10.1117/12.10.1117/1.1427672

KEYWORDS: Luminescence, Cell death, Cancer, Ovarian cancer, Ovary, Fluorescence spectroscopy, Tissues, Control systems, Collagen, In vivo imaging

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Showing 5 of 31 publications

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