Mr. Paulius Danilevicius Profile

Paulius Danilevicius

at Foundation for Research and Technology-Hellas

SPIE Involvement:

Author

Area of Expertise:

direct laser writing , two-photon polymerization , two-photon absorption , z-scan , tissue engineering scaffolds , biomedical devices

Websites:

Company Website | Personal Website

Paulius Danilevicius received his undergraduate degree in 2009 and his Master degree in 2011 from the Faculty of Physics, Vilnius University under the supervision of dr. Mangirdas Malinauskas. From 2012 he applied for PhD studies.
Currently Paulius Danilevicius is a researcher at the Institute of the Electronic Structure and Laser, Foundation for Research and Technology-Hellas in Greece, where he joined in 2011 as a Marie Curie fellow. His main research interests are multiphoton polymerization, direct laser writing of 3D micro-structures and its application in biomedicine and tissue engineering, investigation of non-linear properties of materials.

Proceedings Article | 5 March 2013 Paper

Fabrication, replication, and characterization of microlenses for optofluidic applications

L. Jonusauskas, A. Žukauskas, P. Danilevicius, M. Malinauskas

Proceedings Volume 8613, 861318 (2013) https://doi.org/10.1117/12.2001061

KEYWORDS: Microlens, Sensors, Microlens array, Refractive index, Microfluidics, Microsensors, Lithography, Liquids, Multiphoton lithography, Polymers

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SPIE Journal Paper | 15 May 2012 Open Access

Micro-structured polymer scaffolds fabricated by direct laser writing for tissue engineering

Paulius Danilevicius, Sima Rekštyte, Roaldas Gadonas, Mangirdas Malinauskas, Evaldas Balciunas, Rasa Jarasiene, Daiva Baltriukiene, Virginija Bukelskiene, Antanas Kraniauskas, Raimondas Sirmenis

JBO, Vol. 17, Issue 8, 081405, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.8.081405

KEYWORDS: Polymers, Tissue engineering, In vitro testing, Tissues, Multiphoton lithography, Polymerization, Stem cells, In vivo imaging, Sol-gels, Natural surfaces

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Proceedings Article | 24 December 2011 Paper

Applications of nonlinear laser nano/microlithography: fabrication from nanophotonic to biomedical components

M. Malinauskas, P. Danilevičius, E. Balčiūnas, S. Rekštyté, E. Stankevičius, D. Baltriukienė, V. Bukelskienė, G. Račiukaitis, R. Gadonas

Proceedings Volume 8204, 820407 (2011) https://doi.org/10.1117/12.898982

KEYWORDS: Fabrication, Polymerization, Photopolymers, Polymers, Diffractive optical elements, Laser applications, Biomedical optics, Stem cells, Multiphoton lithography, Nanolithography

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Proceedings Article | 17 May 2010 Paper

Laser two-photon polymerization micro- and nanostructuring over a large area on various substrates

M. Malinauskas, V. Purlys, A. Žukauskas, G. Bickauskaite, T. Gertus, P. Danilevicius, D. Paipulas, M. Rutkauskas, H. Gilbergs, D. Baltriukiene, L. Bukelskis, R. Širmenis, V. Bukelskiene, R. Gadonas, V. Sirvydis, A. Piskarskas

Proceedings Volume 7715, 77151F (2010) https://doi.org/10.1117/12.854507

KEYWORDS: Polymers, 3D modeling, Stem cells, Tissues, Computer aided design, Photopolymers, Nanolithography, Two photon polymerization, Microfluidics, Femtosecond phenomena

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A tightly focused ultrafast pulsed laser beam is guided into the volume of the photosensitive material and induces nonlinear photomodification. By translating the sample, the position of the focus is changed relatively, thus point-by-point complex 3D structures can be written inside the bulk. In this report, we present a Laser Two-Photon Polymerization (LTPP) setup for three-dimensional micro/nanostructuring for applications in photonics, microoptics, micromechanics, microfluidics and biomedicine. This system enables fabrication of functional devices over a large area (up to several cm in lateral size) with reproducible sub-micrometer resolution (up to 200 nm). In our experiments a Yb:KGW active media laser oscillator (75 fs, 200 kW, 515 nm frequency doubled, 80 MHz) was used as an irradiation source. The sample was mounted on XYZ wide range linear motor driven positioning stages having 10 nm positioning resolution. These stages enable an overall travelling range of 100 mm into X and Y directions and 50 mm in Z direction and support a linear scanning speed of up to 300 mm/s. Control of all the equipment was automated via custom made computer software "3D-Poli" specially designed for LTPP applications. The model of the structure can be imported as CAD file, this enables rapid and flexible structuring out of various photopolymers like ORMOCERs, ORMOSILs, acrylates and PEGDAs which are commonly used in conventional UV mask, nanoimprint and μ-stereolithographies. In this paper, we demonstrate polymeric microstructures fabricated over a large area on glass, plastic and metal substrates. This opens a way to produce functional devices like photonic crystals, microlenses, micromechanic and microfluidic components and artificial scaffolds as templates for cell growth. Additionally, results of primary myogenic stem cells expanding on microfabricated polymeric scaffolds are provided. Cell proliferation tests show the material and structure to be biocompatible for the biomedical practice.

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