Dr. Takeaki Ishizawa Profile

Dr. Takeaki Ishizawa

at Univ of Tokyo

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 1 April 2020 Presentation

Applications of intraoperative fluorescence imaging to hepatobiliary and pancreatic surgery (Conference Presentation)

Takeaki Ishizawa, Yasuteru Urano, Kiyoshi Hasegawa

Proceedings Volume 11362, 113620V (2020) https://doi.org/10.1117/12.2559293

Read Abstract +

Recently, in vivo fluorescence imaging using indocyanine green (ICG) has actively been applied to hepatobiliary and pancreatic surgery in clinical settings. 1) Fluorescence cholangiography: fluorescence images of the extrahepatic bile ducts can be obtained by intrabiliary injection of ICG solution (0.025 mg/mL) or preoperative intravenous injection of ICG (2.5 mg). The latter technique begins to be used worldwide for confirmation of the bile duct anatomy during minimally-invasive cholecystectomy. 2) Identification of hepatic tumors: Following preoperative intravenous injection of ICG (0.5 mg/kg), it can accumulate in hepatocellular carcinoma tissues and in non-cancerous hepatic parenchyma surrounding liver metastasis, enabling intraoperative identification of subcapsular hepatic tumors by fluorescence imaging. 3) Hepatic segmentation: ICG solution (0.25 mg/5 mL) is injected into a tumor-bearing portal branch under ultrasound guidance (positive staining). ICG can also be administered intravenously following closure of a corresponding portal pedicle (negative staining). These techniques enables delineation of hepatic segmental boundaries throughout surgical procedures. 4) Assessment of blood perfusion: Fluorescence imaging following intraoperative bolus injection of ICG (2.5mg) visualizes arterial/portal blood flows and perfusion in the surrounding organs during surgeries requiring resection/reconstruction of the major vessels. for intraoperative visualization of biological structures and perfusion assessment. In addition, we have developed a novel fluorophore (glutaryl-phenylalanine hydroxymethyl rhodamine green) activated by pancreatic chymotrypsin for real-time identification of pancreatic juice leakage.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years