The search for new non-invasive methods of research in medicine and physiology is an urgent task of the modern development of human sciences. One of the most attractive options for solving this problem is to recognize the use of human saliva as an object of research. The results obtained confirm that oral fluid facies is a simple, noninvasive, lowcost method for additional assessment of the human organism’s functional state, applicable to the population mass screening. The morphological picture of the oral fluid facies and the results of its computer morphometry are consistently combined with the human level of general nonspecific reactivity of an organism (LGNRO) and have a distinct circadian dynamics of the main parameters. The qualitative characteristics analysis of the facies’ peripheral zone (size and homogeneous protein deposits, the structure of the boundary between the outer and inner zones) and their quantitative equivalents (thickness and intensity of crystal formation) have been proved to be the most informative when analyzing the human oral fluid facies
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