Surface Plasmon resonance (SPR) technique is gradually growing as a research focus in optical area, which has been widely applied in many disciplines. The fiber-based SPR sensor, combining the advantages of fiber and SPR phenomenon, will lead to more tremendous application areas. The design and fabrication of different fiber SPR sensors are always be focuses of researchers in recent year, but the characteristic wavelength demodulation of the SPR sensor didn’t obtain enough attention. In this paper, the detection system for a fiber-based SPR sensor was presented first, and the detection mechanism of the refractive index sensing was obtained theoretically. Based on the theoretical simulation and analysis, the analytical expression of the all-phase low-pass filters was deduced, which is used for the de-noising of the original spectrum for the SPR sensing system, leading to resonance wavelength extraction only by calculating the derivative of the de-noised signal. So the resonance wavelength of the SPR sensor can be easily obtained by using this simple demodulation algorithm. Based on the realization of the system, the refractive index sensing of alcohol solution was carried out. And a good linear relationship between the refractive index of the solution and the characteristic wavelength of the SPR sensor can be obtained, with refractive index sensitivity and fitting error of 2048.5 nm/RIU and 5.69 nm respectively.
KEYWORDS: Glucose, Spectroscopy, Blood, Absorption, Mid-IR, In vitro testing, In vivo imaging, Attenuated total reflectance, Signal detection, Spectroscopes
Glucose specificity is the premise of spectroscopic measurements for blood glucose concentration, and it is also
paramount for feasibility study of a spectral measurement method. Two-dimensional correlation spectroscopy
technology is widely used in many fields such as inter-/intra-molecular reaction, material phase transition and
information extraction because of its high resolution and the effective "sequential order" rules (Noda's rule). By using 2D
correlation spectroscopy analysis, we aim at exploring glucose specificity for noninvasive glucose measurements from
mid-infrared spectra collected from human beings. The study is mainly divided into two parts. The first part is to prove
the realizability of the method by 2D correlation analysis of in vitro solutions which all contain glucose. And the second
part is validating characteristic information of glucose from mid-infrared ATR spectra of human fingers by use of the 2D
correlation spectroscopy technology. The conclusion is that glucose specific spectral information is really present in
noninvasive mid-infrared in vivo spectra. So the feasibility of mid-infrared spectroscopy in noninvasive measurements of
blood glucose concentration is demonstrated fundamentally.
This paper proposes a new image super-resolution restoration algorithm. The development of the algorithm is based on the improvement of the classical projection on convex set (POCS) algorithm and wavelet fusion to restore a super-resolution image from a series of low resolution (LR) images. At first, the POCS iteration is used to restore high-resolution (HR) image from every LR image. Then several different rules are chosen to fuse HR images in wavelet domain, and a HR image is reconstructed by inverse wavelet transform. The reconstructed image is evaluated by entropy, cross entropy, definition and the peak signal-noise ratio. The experimental results of the processed CT images showed that this method can improve the ability of fusing different image information, and the texture of the image is more prominent, the image quality is higher.
KEYWORDS: Databases, Network architectures, Digital signal processing, Human-machine interfaces, Medical equipment, Data centers, Patents, Manufacturing, Local area networks, Medical imaging
In this paper, the development trend of medical monitor system is analyzed and portable trend and network function
become more and more popular among all kinds of medical monitor devices. The architecture of medical network
monitor system solution is provided and design and implementation details of medical monitor terminal, monitor center
software, distributed medical database and two kind of medical information terminal are especially discussed.
Rabbit3000 system is used in medical monitor terminal to implement security administration of data transfer on network,
human-machine interface, power management and DSP interface while DSP chip TMS5402 is used in signal analysis
and data compression. Distributed medical database is designed for hospital center according to DICOM information
model and HL7 standard. Pocket medical information terminal based on ARM9 embedded platform is also developed to
interactive with center database on networks. Two kernels based on WINCE are customized and corresponding terminal
software are developed for nurse's routine care and doctor's auxiliary diagnosis. Now invention patent of the monitor
terminal is approved and manufacture and clinic test plans are scheduled. Applications for invention patent are also
arranged for two medical information terminals.
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