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4 March 2019 Towards lens-based wavefront sensorless adaptive optics full-field OCT for in-vivo retinal imaging (Conference Presentation)
Pedro Mecê, Peng Xiao, Viacheslav Mazlin, Jules Scholler, Kate Grieve, José-Alain Sahel, Mathias Fink, Claude Boccara
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Proceedings Volume 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII; 1086722 (2019) https://doi.org/10.1117/12.2508630
Event: SPIE BiOS, 2019, San Francisco, California, United States
Abstract
Full-Field Optical Coherence Tomography (FF-OCT) offers aberration independent resolution. This inherent property makes FF-OCT a promising imaging modality for 3D high-resolution retinal imaging. Nevertheless, ocular aberrations affect signal reduction, imposing Adaptive Optics. Here we investigate the best strategy to compensate for ocular aberrations in our FF-OCT setup, in terms of wavefront measurement and correction. The use of wavefront sensorless approach based on the FF-OCT signal level is investigated. Moreover, a strategy of static wavefront correction in a non-conjugated pupil plane and next to the eye’s pupil, just like spectacles, favoring a compact and non-complex AO design, is also investigated. Additionally, the use of wavefront corrector devices such as an adaptive liquid lens (correcting to defocus and astigmatism) and multi-actuator adaptive lenses (correcting up to the 4th order Zernike polynomial) are evaluated. Finally, we expect the implementation of one or a combination of the studied strategies into our FF-OCT setup to lead to the first in-vivo retinal images obtained using AO-assisted FF-OCT, for different retinal layers with enhanced SNR and a 3D high-resolution.
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Pedro Mecê, Peng Xiao, Viacheslav Mazlin, Jules Scholler, Kate Grieve, José-Alain Sahel, Mathias Fink, and Claude Boccara "Towards lens-based wavefront sensorless adaptive optics full-field OCT for in-vivo retinal imaging (Conference Presentation)", Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 1086722 (4 March 2019); https://doi.org/10.1117/12.2508630
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KEYWORDS
In vivo imaging
Optical coherence tomography
Retinal scanning
Wavefronts
3D image processing
Adaptive optics
3D metrology
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