Photodynamic therapy of lung cancer

U. A. Ablitsov; M. I. Kuzin; L. E. Loginov; L. V. Uspensky; V. K. Rybin; Kirill G. Linkov; Victor B. Loschenov; Gennadii A. Meerovich; Alexander A. Stratonnikov; Nadezgda L. Torshina; Georgy N. Vorozhtsov; Rudolf W. Steiner

doi:10.1117/12.230994

31 January 1996 Photodynamic therapy of lung cancer

U. A. Ablitsov, M. I. Kuzin, L. E. Loginov, L. V. Uspensky, V. K. Rybin, Kirill G. Linkov, Victor B. Loschenov, Gennadii A. Meerovich, Alexander A. Stratonnikov, Nadezgda L. Torshina, Georgy N. Vorozhtsov, Rudolf W. Steiner

Author Affiliations +

Proceedings Volume 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities; (1996) https://doi.org/10.1117/12.230994
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

Photodynamic therapy (PDT) with the use of laser endoscopic spectrum analyzer (LESA-5), spectral-analyzing video-imaging system, Kr laser and various types of catheters for different tumor localizations, and Phthalocyanine aluminum photosensitizers in patients with lung cancer was discussed. PDT was carried out in twenty patients with lung cancer. Usually we used 1 - 3 seances of laser treatment 10 - 30 minutes long. Concentration of photosensitizer in normal and malignant tissue was controlled by LESA-5. Treatment was monitored by spectral- analyzing video-imaging system in fluorescent light. The results show high efficiency of PDT especially in patients with early lung cancer (necrosis of all tumor mass, i.e. complete regression of tumor). For all other patients we obtained partial regression of lung cancer.

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U. A. Ablitsov, M. I. Kuzin, L. E. Loginov, L. V. Uspensky, V. K. Rybin, Kirill G. Linkov, Victor B. Loschenov, Gennadii A. Meerovich, Alexander A. Stratonnikov, Nadezgda L. Torshina, Georgy N. Vorozhtsov, and Rudolf W. Steiner "Photodynamic therapy of lung cancer", Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); https://doi.org/10.1117/12.230994

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