Polymeric microfluidic device for separation of small molecules

Jun Kameoka; Hongwei Zhong; Jack Henion; Harold G. Craighead

doi:10.1117/12.443062

28 September 2001 Polymeric microfluidic device for separation of small molecules

Jun Kameoka, Hongwei Zhong, Jack Henion, Harold G. Craighead

Proceedings Volume 4560, Microfluidics and BioMEMS; (2001) https://doi.org/10.1117/12.443062
Event: Micromachining and Microfabrication, 2001, San Francisco, CA, United States

Abstract

We have used an embossed plastic microfluidic system for the electrophoretic separation of relatively small molecules followed by electro spray ionization of the analytes. Th separation of dyes has been also visualized in microfluidic systems. A lithographically produced silicon master was used to emboss channels in ZEONOR 1020R plastic. An oxygen plasma was used to convert the plastic channel surface from hydrophobic to hydrophilic characteristics for the separation of molecules in aqueous solution.

Citation Download Citation

Jun Kameoka, Hongwei Zhong, Jack Henion, and Harold G. Craighead "Polymeric microfluidic device for separation of small molecules", Proc. SPIE 4560, Microfluidics and BioMEMS, (28 September 2001); https://doi.org/10.1117/12.443062

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