Design and characterization of a multi-channel time-gated diffuse correlation spectroscopy system at 1064nm

Marco Renna; Jonathan M. Richardson; George Jordy; Tom Cheng; Mitchell Robinson; Nisan Ozana; Dibbyan Mazumder; Niyom Lue; Brian Aull; Bernhard Zimmerman; Stefan Carp; Erik Duerr; David Boas; Maria Angela Franceschini; Megan Blackwell

doi:10.1117/12.2610207

2 March 2022 Design and characterization of a multi-channel time-gated diffuse correlation spectroscopy system at 1064nm

Marco Renna, Jonathan M. Richardson, George Jordy, Tom Cheng, Mitchell Robinson, Nisan Ozana, Dibbyan Mazumder, Niyom Lue, Brian Aull, Bernhard Zimmerman, Stefan Carp, Erik Duerr, David Boas, Maria Angela Franceschini, Megan Blackwell

Author Affiliations +

Proceedings Volume PC11959, Dynamics and Fluctuations in Biomedical Photonics XIX; PC1195908 (2022) https://doi.org/10.1117/12.2610207
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

We present the design of an innovative instrument for time-gated diffuse correlation spectroscopy. It features a 1064nm pulsed sub-ns long coherence-length laser operating up to 75MHz, a 100-channel in-FPGA correlator and a novel time-gated 32×32 InP/InGaAs-based Single Photon Avalanche Diode (SPAD) array with sub-nanosecond gating capabilities operating up to 10MHz repetition rate. We present components experimental characterization and preliminary validations on a liquid phantom. This testing is informing us for a revision of the photodetector which will allow to reach up to 192 optical channels towards functional blood flow changes measurements with full head coverage.

Conference Presentation

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Marco Renna, Jonathan M. Richardson, George Jordy, Tom Cheng, Mitchell Robinson, Nisan Ozana, Dibbyan Mazumder, Niyom Lue, Brian Aull, Bernhard Zimmerman, Stefan Carp, Erik Duerr, David Boas, Maria Angela Franceschini, and Megan Blackwell "Design and characterization of a multi-channel time-gated diffuse correlation spectroscopy system at 1064nm", Proc. SPIE PC11959, Dynamics and Fluctuations in Biomedical Photonics XIX, PC1195908 (2 March 2022); https://doi.org/10.1117/12.2610207

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