Attenuation-corrected fluorescence extraction for image-guided surgery in spatial frequency domain

Bin Yang; Manu Sharma; James W. Tunnell

doi:10.1117/1.JBO.18.8.080503

16 August 2013 Attenuation-corrected fluorescence extraction for image-guided surgery in spatial frequency domain

Bin Yang, Manu Sharma, James W. Tunnell

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Journal of Biomedical Optics, Vol. 18, Issue 8, 080503 (August 2013). https://doi.org/10.1117/1.JBO.18.8.080503

Abstract

A new approach to retrieve the attenuation-corrected fluorescence using spatial frequency-domain imaging is demonstrated. Both in vitro and ex vivo experiments showed the technique can compensate for the fluorescence attenuation from tissue absorption and scattering. This approach has potential in molecular image-guided surgery.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Bin Yang, Manu Sharma, and James W. Tunnell "Attenuation-corrected fluorescence extraction for image-guided surgery in spatial frequency domain," Journal of Biomedical Optics 18(8), 080503 (16 August 2013). https://doi.org/10.1117/1.JBO.18.8.080503

Published: 16 August 2013

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