Dr. David J. Cuccia Profile

Dr. David J. Cuccia

President, CTO at Modulim

SPIE Involvement:

Conference Program Committee | Author

Publications (28)

SPIE Journal Paper | 12 April 2022 Open Access

MCCL: an open-source software application for Monte Carlo simulations of radiative transport

Carole Hayakawa, Lisa Malenfant, Janaka Ranasinghesagara, David Cuccia, Jerome Spanier, Vasan Venugopalan

JBO, Vol. 27, Issue 08, 083005, (April 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.8.083005

KEYWORDS: Monte Carlo methods, Sensors, Tissues, Tissue optics, Databases, Reflectivity, Interfaces, Absorption, Natural surfaces, Computer simulations

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Proceedings Article | 7 March 2022 Presentation

Widefield imaging of deep and superficial hemodynamics during an arterial vascular occlusion of the volar forearm

Gordon Kennedy, Rebecca Rowland, Amaan Mazhar, David Cuccia, Anthony Durkin

Proceedings Volume PC11934, PC1193401 (2022) https://doi.org/10.1117/12.2610540

KEYWORDS: Oxygen, Ischemia, Image analysis, Data acquisition, Hemodynamics, Tissues, Near infrared spectroscopy

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SPIE Journal Paper | 19 July 2019 Open Access

Special Section Guest Editorial: Special Section on Spatial Frequency Domain Imaging

Sylvain Gioux, Amaan Mazhar, Anthony Durkin, Bruce Tromberg, David Cuccia

JBO, Vol. 24, Issue 07, 071601, (July 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.7.071601

KEYWORDS: Optical properties, Instrument modeling, Imaging systems, Medical laser equipment, Laser tissue interaction, Tissues, Biomedical optics, Light scattering, Scattering, Machine learning

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SPIE Journal Paper | 20 June 2019 Open Access

Spatial frequency domain imaging in 2019: principles, applications, and perspectives

Sylvain Gioux, Amaan Mazhar, David J. Cuccia

JBO, Vol. 24, Issue 07, 071613, (June 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.7.071613

KEYWORDS: Optical properties, Tissues, Spatial frequencies, Scattering, Absorption, Luminescence, Imaging systems, Calibration, Modulation transfer functions, Diffuse reflectance spectroscopy

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SPIE Journal Paper | 10 November 2018 Open Access

Correcting Cherenkov light attenuation in tissue using spatial frequency domain imaging for quantitative surface dosimetry during whole breast radiation therapy

Rachael Hachadorian, Petr Bruza, Michael Jermyn, Amaan Mazhar, David Cuccia, Lesley Jarvis, David Gladstone, Brian Pogue

JBO, Vol. 24, Issue 07, 071609, (November 2018) https://doi.org/10.1117/12.10.1117/1.JBO.24.7.071609

KEYWORDS: Tissue optics, Signal attenuation, Optical properties, Radiotherapy, Natural surfaces, Imaging systems, Blood, Calibration, Breast, Tissues

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SPIE Journal Paper | 22 August 2014 Open Access

Noncontact imaging of burn depth and extent in a porcine model using spatial frequency domain imaging

Amaan Mazhar, Steve Saggese, Alonda Pollins, Nancy Cardwell, Lillian Nanney, David Cuccia

JBO, Vol. 19, Issue 08, 086019, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.086019

KEYWORDS: Scattering, Tissues, Injuries, Absorption, Tissue optics, Collagen, Reflectivity, Optical properties, Imaging systems, Near infrared

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SPIE Journal Paper | 22 March 2013 Open Access

System analysis of spatial frequency domain imaging for quantitative mapping of surgically resected breast tissues

Ashley Laughney, Venkataramanan Krishnaswamy, Tyler Rice, David Cuccia, Richard Barth, Bruce Tromberg, Keith Paulsen, Brian Pogue, Wendy Wells

JBO, Vol. 18, Issue 03, 036012, (March 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.3.036012

KEYWORDS: Scattering, Tissues, Imaging systems, Absorption, Breast, Diffusion, Modulation, Light scattering, Spatial frequencies, Surgery

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Proceedings Article | 13 March 2013 Paper

Component and system evaluation for the development of a handheld point-of-care spatial frequency domain imaging (SFDI) device

K. Nadeau, P. Khoury, A. Mazhar, D. Cuccia, A. Durkin

Proceedings Volume 8573, 857304 (2013) https://doi.org/10.1117/12.2004909

KEYWORDS: Light emitting diodes, Near infrared, Cameras, Projection systems, Light sources, Imaging systems, Point-of-care devices, Tissue optics, Charge-coupled devices, Calibration

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SPIE Journal Paper | 18 July 2012 Open Access

Diffuse optical imaging using spatially and temporally modulated light

Thomas O'Sullivan, Albert Cerussi, Bruce Tromberg, David Cuccia

JBO, Vol. 17, Issue 7, 071311, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.071311

KEYWORDS: Tissues, Scattering, Absorption, Modulation, Tumors, Light scattering, Optical properties, Diffuse optical imaging, Chromophores, Reflectivity

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Proceedings Article | 13 February 2012 Paper

Implementation of an LED-based clinical spatial frequency domain imaging system

Amaan Mazhar, Seyed Sharif, Steve Saggese, Bernard Choi, David Cuccia, Anthony Durkin

Proceedings Volume 8254, 82540A (2012) https://doi.org/10.1117/12.909813

KEYWORDS: Optical properties, Absorption, Tissues, Light emitting diodes, Imaging systems, Scattering, Chromophores, Tissue optics, Skin, Oxygen

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Proceedings Article | 13 February 2012 Paper

Spatial frequency domain imaging (SFDI): a technology overview and validation of an LED-based clinic friendly device

David Cuccia

Proceedings Volume 8254, 825405 (2012) https://doi.org/10.1117/12.908860

KEYWORDS: Tissues, Modulation, Near infrared, Scattering, Optical properties, Tissue optics, In vivo imaging, Oxygen, Instrument modeling, Thermal modeling

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SPIE Journal Paper | 1 December 2011 Open Access

Effects of motion on optical properties in the spatial frequency domain

John Quan Nguyen, Rolf Saager, Anthony Durkin, David Cuccia, Kristen Kelly, James Jakowatz, David Hsiang

JBO, Vol. 16, Issue 12, 126009, (December 2011) https://doi.org/10.1117/12.10.1117/1.3662454

KEYWORDS: Optical properties, Absorption, Phase shifts, Skin, Spatial frequencies, Motion measurement, Demodulation, Tissue optics, Scattering, Chromophores

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SPIE Journal Paper | 1 December 2011 Open Access

Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain

Rolf Saager, Anthony Durkin, David Cuccia, Steve Saggese, Kristen Kelly

JBO, Vol. 16, Issue 12, 126013, (December 2011) https://doi.org/10.1117/12.10.1117/1.3665440

KEYWORDS: Luminescence, Optical properties, Tissue optics, Absorption, In vivo imaging, Tissues, Signal detection, Scattering, Reflectivity, Liquids

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SPIE Journal Paper | 1 August 2011 Open Access

First-in-human pilot study of a spatial frequency domain oxygenation imaging system

Sylvain Gioux, Alan Stockdale, Rafiou Oketokoun, Yoshitomo Ashitate, Nicholas Durr, Lorissa Moffitt, John Frangioni, Amaan Mazhar, Bruce Tromberg, Anthony Durkin, Bernard Lee, Samuel Lin, Adam Tobias, David Cuccia, Edward Kelly, Maxwell Weinmann

JBO, Vol. 16, Issue 08, 086015, (August 2011) https://doi.org/10.1117/12.10.1117/1.3614566

KEYWORDS: Imaging systems, Tissues, Surgery, Skin, Light sources, Near infrared, Digital micromirror devices, Oxygen, Chromophores, Optical properties

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SPIE Journal Paper | 1 July 2011 Open Access

Method for depth-resolved quantitation of optical properties in layered media using spatially modulated quantitative spectroscopy

Rolf Saager, Alex Truong, Anthony Durkin, David Cuccia

JBO, Vol. 16, Issue 07, 077002, (July 2011) https://doi.org/10.1117/12.10.1117/1.3597621

KEYWORDS: Optical properties, Absorption, Scattering, Tissue optics, Monte Carlo methods, Skin, Chromophores, Visible radiation, Spectroscopy, Tissues

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Proceedings Article | 18 February 2011 Paper

Motion correction in spatial frequency domain imaging; optical property determination in pigmented lesions

John Quan Nguyen, Rolf Saager, David Cuccia, Kristen Kelly, David Hsiang, Anthony Durkin

Proceedings Volume 7883, 78830P (2011) https://doi.org/10.1117/12.876720

KEYWORDS: Absorption, Skin, Phase shifts, Motion measurement, Optical properties, Demodulation, Scattering, Tissue optics, Melanoma, Edge detection

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Proceedings Article | 17 February 2011 Open Access

Preclinical and clinical validation of a novel oxygenation imaging system

Sylvain Gioux, Amaan Mazhar, Bernard Lee, David Cuccia, Alan Stockdale, Rafiou Oketokoun, Yoshitomo Ashitate, Nicholas Durr, Anthony Durkin, Bruce Tromberg, John Frangioni

Proceedings Volume 7896, 78961R (2011) https://doi.org/10.1117/12.875603

KEYWORDS: Imaging systems, Surgery, Near infrared, Cameras, Optical properties, Light sources, Skin, Tissues, Oxygen, Diodes

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SPIE Journal Paper | 1 January 2011 Open Access

Real-time blood flow visualization using the graphics processing unit

Owen Yang, David Cuccia, Bernard Choi

JBO, Vol. 16, Issue 1, 016009, (January 2011) https://doi.org/10.1117/12.10.1117/1.3528610

KEYWORDS: Image processing, Speckle, Visualization, LabVIEW, Blood circulation, Image visualization, Video, Graphics processing units, Cameras, Video acceleration

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SPIE Journal Paper | 1 January 2011 Open Access

Multispectral imaging of tissue absorption and scattering using spatial frequency domain imaging and a computed-tomography imaging spectrometer

Jessie Weber, Anthony Durkin, Bruce Tromberg, David Cuccia, William Johnson, Daniel Wilson, Gregory Bearman, Mike Hsu, Alexander Lin, Devin Binder

JBO, Vol. 16, Issue 1, 011015, (January 2011) https://doi.org/10.1117/12.10.1117/1.3528628

KEYWORDS: Absorption, Scattering, Tissue optics, Tissues, Spatial frequencies, Optical properties, Multispectral imaging, Spectroscopy, Brain mapping, Brain

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SPIE Journal Paper | 1 November 2010 Open Access

Wavelength optimization for rapid chromophore mapping using spatial frequency domain imaging

Amaan Mazhar, Steven Dell, David Cuccia, Sylvain Gioux, Anthony Durkin, John Frangioni, Bruce Tromberg

JBO, Vol. 15, Issue 06, 061716, (November 2010) https://doi.org/10.1117/12.10.1117/1.3523373

KEYWORDS: Chromophores, Hemodynamics, Tissues, Condition numbers, Absorption, In vivo imaging, Scattering, Computer simulations, Light emitting diodes, Light scattering

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SPIE Journal Paper | 1 May 2010 Open Access

Lookup-table method for imaging optical properties with structured illumination beyond the diffusion theory regime

Tim Erickson, Amaan Mazhar, David Cuccia, Anthony Durkin, James Tunnell

JBO, Vol. 15, Issue 03, 036013, (May 2010) https://doi.org/10.1117/12.10.1117/1.3431728

KEYWORDS: Optical properties, Modulation, Reflectivity, Scattering, Absorption, Optical spheres, Photons, Diffusion, Tissue optics, Optical imaging

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SPIE Journal Paper | 1 January 2010 Open Access

Determination of optical properties of turbid media spanning visible and near-infrared regimes via spatially modulated quantitative spectroscopy

Rolf Saager, David Cuccia, Anthony Durkin

JBO, Vol. 15, Issue 01, 017012, (January 2010) https://doi.org/10.1117/12.10.1117/1.3299322

KEYWORDS: Absorption, Optical properties, Scattering, Reflectivity, Spatial frequencies, Chromophores, Tissue optics, Visible radiation, Tissues, Skin

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SPIE Journal Paper | 1 January 2010 Open Access

Structured illumination enhances resolution and contrast in thick tissue fluorescence imaging

Amaan Mazhar, David Cuccia, Sylvain Gioux, Anthony Durkin, John Frangioni, Bruce Tromberg

JBO, Vol. 15, Issue 01, 010506, (January 2010) https://doi.org/10.1117/12.10.1117/1.3299321

KEYWORDS: Luminescence, Spatial frequencies, Image resolution, Spatial resolution, Modulation, Tissues, Video, Tissue optics, Near infrared, Structured light

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SPIE Journal Paper | 1 May 2009 Open Access

Three-dimensional surface profile intensity correction for spatially modulated imaging

Sylvain Gioux, Amaan Mazhar, David Cuccia, Anthony Durkin, Bruce Tromberg, John Frangioni

JBO, Vol. 14, Issue 03, 034045, (May 2009) https://doi.org/10.1117/12.10.1117/1.3156840

KEYWORDS: Optical properties, Absorption, Scattering, Calibration, Spatial frequencies, Modulation, Optical testing, Data acquisition, Tissue optics, 3D image processing

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SPIE Journal Paper | 1 March 2009 Open Access

Quantitation and mapping of tissue optical properties using modulated imaging

David Cuccia, Frédéric Bevilacqua, Anthony Durkin, Frederick Ayers, Bruce Tromberg

JBO, Vol. 14, Issue 02, 024012, (March 2009) https://doi.org/10.1117/12.10.1117/1.3088140

KEYWORDS: Absorption, Scattering, Optical properties, Spatial frequencies, Diffusion, Reflectivity, Modulation, Diffuse reflectance spectroscopy, Tissue optics, Monte Carlo methods

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Proceedings Article | 21 February 2008 Paper

Fabrication and characterization of silicone-based tissue phantoms with tunable optical properties in the visible and near infrared domain

Frederick Ayers, Alex Grant, Danny Kuo, David Cuccia, Anthony Durkin

Proceedings Volume 6870, 687007 (2008) https://doi.org/10.1117/12.764969

KEYWORDS: Scattering, Absorption, Silicon, Tissue optics, Optical properties, Near infrared, Visible radiation, Tissues, Calibration, Titanium dioxide

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Proceedings Article | 23 March 2007 Open Access

Mapping tissue chromophore changes in cerebral ischemia: a pilot study

David Abookasis, Marlon Mathews, Christopher Lay, David Cuccia, Ron Frostig, Mark Linskey, Bruce Tromberg

Proceedings Volume 6424, 64242J (2007) https://doi.org/10.1117/12.718430

KEYWORDS: Brain, Chromophores, Ischemia, Brain mapping, Modulation, Oxygen, Tissues, Tissue optics, Arteries, CCD cameras

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Proceedings Article | 6 February 2007 Paper

Detection of bruises on golden delicious apples using spatial-frequency-domain imaging

Eric Anderson, David Cuccia, Anthony Durkin

Proceedings Volume 6430, 64301O (2007) https://doi.org/10.1117/12.717608

KEYWORDS: Scattering, Absorption, Reflectivity, Optical properties, Light scattering, Imaging systems, Spatial frequencies, Biomedical optics, Optical imaging, Digital micromirror devices

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