Dr. Jacques Van Dam Profile

Dr. Jacques Van Dam

at Univ of Southern California

SPIE Involvement:

Author

Publications (10)

Proceedings Article | 2 March 2015 Paper

Integrated OCT-US catheter for detection of cancer in the gastrointestinal tract

Jiawen Li, Teng Ma, Thomas Cummins, K. Kirk Shung, Jacques Van Dam, Qifa Zhou, Zhongping Chen

Proceedings Volume 9304, 93040Z (2015) https://doi.org/10.1117/12.2074697

KEYWORDS: Optical coherence tomography, Cancer, Simulation of CCA and DLA aggregates, Tumors, Pancreatic cancer, Imaging systems, Lens design, Visualization, Reflection, Lymphatic system

Read Abstract +

Proceedings Article | 1 March 2008 Paper

Improving colorectal cancer screening: fact and fantasy

Jacques Van Dam

Proceedings Volume 6864, 68640C (2008) https://doi.org/10.1117/12.762449

KEYWORDS: Colorectal cancer, Optical coherence tomography, Colon, Luminescence, Tissue optics, Endoscopy, Tissues, Spectroscopy, Biopsy, Fluorescence spectroscopy

Read Abstract +

Premalignant diseases of the gastrointestinal tract, such as Barrett's esophagus, long-standing ulcerative colitis, and adenomatous polyps, have a significantly increased risk for development of adenocarcinoma, most often through an intermediate stage of dysplasia. Adenocarcinoma of the colon is the second most common cancer in the United States. Because patients with colorectal cancer often present with advanced disease, the outcomes are associated with significant morbidity and mortality. Effective methods of early detection are essential. As non-polypoid dysplasia is not visible using conventional endoscopy, surveillance of patients with Barrett's esophagus and ulcerative colitis is performed via a system in which multiple random biopsies are obtained at prescribed intervals. Sampling error and missed diagnoses occur frequently and render current screening methods inadequate. Also, the examination of a tissue biopsy is time consuming and costly, and significant intra- and inter-observer variation may occur. The newer methods discussed herein demonstrate the potential to solve these problems by early detection of disease with high sensitivity and specificity. Conventional endoscopy is based on the observation of white light reflected off the tissue surface. Subtle changes in color and shadow reveal structural changes. New developments in optical imaging go beyond white light, exploiting other properties of light. Several promising methods will be discussed at this meeting and shall be briefly discussed below. However, few such imaging modalities have arrived at our clinical practice. Some much more practical methods to improve colorectal cancer screening are currently being evaluated for their clinical impact. These methods seek to overcome limitations other than those of detecting dysplasia not visible under white light endoscopy. The current standard practice of colorectal cancer screening utilizes colonoscopy, an uncomfortable, sometimes difficult medical procedure. Efforts to improve the practice of colonoscopy will be described. Another limitation of the current practice is the inability to detect polypoid neoplasia that is hidden from view under white light imaging by the natural folds that occur within the colon. A device to overcome this limitation will also be described. Efforts to improve colorectal cancer screening (and thereby decrease the death rate of this second leading cause of cancer death in the United States) are progressing in many arenas. The researcher, basic or clinical, should maintain an up to date overview of the field and how each new technological advance is likely to have a role in the screening and early detection of colorectal cancer.

SPIE Journal Paper | 1 April 2006

Stereoscopic vision system

Zsolt Király, George Springer, Jacques Van Dam

OE, Vol. 45, Issue 04, 043006, (April 2006) https://doi.org/10.1117/12.10.1117/1.2189856

KEYWORDS: Cameras, Video, Microcontrollers, Switches, Sensors, Stereo vision systems, Optical engineering, Distortion, Multiplexers, Camera shutters

Read Abstract +

Proceedings Article | 15 July 1999 Paper

Quantitative analysis of mucosal tissues in patients using light scattering spectroscopy

Lev Perelman, George Zonios, Vadim Backman, Rajan Gurjar, Irving Itzkan, Ramachandra Dasari, Jacques Van Dam, Michael Feld

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356844

KEYWORDS: Tissues, Scattering, Diffuse reflectance spectroscopy, Absorption, Light scattering, Refractive index, Polarization, Spectroscopy, Tissue optics, Cancer

Read Abstract +

Proceedings Article | 10 April 1998 Paper

Real-time in-vivo endoscopic imaging of fluorescence from human colonic adenomas

Thomas Wang, Jacques Van Dam, James Crawford, Yang Wang, Irving Itzkan, Michael Feld

Proceedings Volume 3259, (1998) https://doi.org/10.1117/12.307335

KEYWORDS: Luminescence, Image processing, Endoscopy, In vivo imaging, Biopsy, Endoscopes, Charge-coupled devices, In vitro testing, Optical fibers, Fluorescence spectroscopy

Read Abstract +

Proceedings Article | 8 May 1995 Paper

Laser-induced fluorescence spectroscopy of colonic dysplasia: prospects for optical histological analysis

Ramasamy Manoharan, George Zonios, Robert Cothren, Joseph Arendt, Jacques Van Dam, Michael Feld

Proceedings Volume 2388, (1995) https://doi.org/10.1117/12.208501

KEYWORDS: Tissues, Luminescence, Laser induced fluorescence, Fluorescence spectroscopy, Collagen, Spectroscopy, Laser spectroscopy, Colon, Absorption, Signal attenuation

Read Abstract +

Proceedings Article | 30 March 1995 Paper

Laser-induced fluorescence endoscopic imaging for detection of colonic dysplasia

Thomas Wang, Yang Wang, Jacques Van Dam, James Crawford, Elizabeth Preisinger, Michael Feld

Proceedings Volume 2390, (1995) https://doi.org/10.1117/12.205987

KEYWORDS: Laser induced fluorescence, Tissues, Tissue optics, Endoscopy, Image processing, Laser induced plasma spectroscopy, Colon, Fiber optics, Optical fibers, Near ultraviolet

Read Abstract +

Proceedings Article | 1 March 1995 Paper

Fluorescence spectroscopy for colon cancer diagnosis

George Zonios, Robert Cothren, Joseph Arendt, Jun Wu, James Crawford, Jacques Van Dam, Ramasamy Manoharan, Michael Feld

Proceedings Volume 2371, (1995) https://doi.org/10.1117/12.203411

KEYWORDS: Fluorescence spectroscopy, Tissue optics, Luminescence, Colorectal cancer, Laser induced fluorescence, Laser spectroscopy, Spectroscopy, In vivo imaging, Laser tissue interaction, Imaging spectroscopy

Read Abstract +

Proceedings Article | 4 January 1995 Paper

Fluorescence spectroscopy for colon cancer diagnosis

George Zonios, Robert Cothren, Joseph Arendt, Jun Wu, James Crawford, Jacques Van Dam, Ramasamy Manoharan, Michael Feld

Proceedings Volume 2324, (1995) https://doi.org/10.1117/12.198726

KEYWORDS: Luminescence, Tissues, Tissue optics, Laser induced fluorescence, Fluorescence spectroscopy, Colorectal cancer, Diagnostics, Colon, Absorption, Spectroscopy

Read Abstract +

Proceedings Article | 22 December 1994 Paper

Raman spectroscopy for cancer detection: instrument development and tissue diagnosis

Ramasamy Manoharan, Yang Wang, Nada Boustany, James Brennan, Joseph Baraga, Ramachandra Dasari, Jacques Van Dam, Samuel Singer, Michael Feld

Proceedings Volume 2328, (1994) https://doi.org/10.1117/12.197502

KEYWORDS: Raman spectroscopy, Tissues, Ultraviolet radiation, Tissue optics, Luminescence, Near infrared, Cancer, Tumors, Proteins, Sapphire lasers

Read Abstract +

Showing 5 of 10 publications

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years