Prof. Manfred D. Kessler Profile

Prof. Manfred D. Kessler

Director at Friedrich-Alexander-Univ Erlangen-Nürnberg

SPIE Involvement:

Author

Publications (49)

Proceedings Article | 1 May 2007 Paper

Paper

Changes in capillary filling do not influence inspiratory-induced vasoconstrictive episodes

Elke Ochsmann, Robert Rauh, Michael Mueck-Weymann, Manfred Kessler

Proceedings Volume 6535, 65350M (2007) https://doi.org/10.1117/12.740811

KEYWORDS: Capillaries, Doppler effect, Physiology, Nervous system, Spectrophotometry, Diagnostics, Semiconductor lasers, Signal detection, Medicine, Skin

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Proceedings Article | 5 June 2002 Paper

Paper

Imaging and learning in back-scattered light by artificial neural networks

Dumitru Nastac, Paul Cristea, Manfred Kessler, Razvan Matei

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469473

KEYWORDS: Neural networks, Artificial neural networks, Spectrophotometry, Physiology, Cardiology, Tissues, Tissue optics, Artificial intelligence, Neurons, Distance measurement

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Proceedings Article | 5 June 2002 Paper

Paper

EMPHO-oxyscan spectrometer for 2D- and 3D-imaging in VIS and NIR

Barbara Albert-Hehn, Paul Cristea, Manfred Kessler, Dumitru Nastac

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469439

KEYWORDS: Spectroscopy, Optical sensors, Near infrared, Liver, Tissues, Physiology, Capillaries, Waveguides, Pathophysiology, Transplantation

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Proceedings Article | 5 June 2002 Paper

Paper

Explanation of prerequisites for patient monitoring

Michael Singer, Manfred Kessler, Robert Rauh

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469456

KEYWORDS: Tissue optics, Tissues, Heart, Oxygen, Sensors, Liver, Capillaries, Optical testing, Calibration, Physiology

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Proceedings Article | 5 June 2002 Paper

Paper

Drug effects on functional structures in isolated perfused pig heart

Tobias Trinks, Michael Hiller, Manfred Kessler, Robert Rauh

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469453

KEYWORDS: Heart, Oxygen, Tissues, Calcium, Arteries, Waveguides, Visualization, 3D modeling, Instrument modeling, Blood

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Proceedings Article | 5 June 2002 Paper

Paper

Functional monitoring in perfused liver

Markus Boehnert, Manfred Kessler, Andre Nicklas, Michael Singer

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469460

KEYWORDS: Near infrared, Liver, Tissues, Blood, Absorption, Visible radiation, Oxygen, Optical testing, Heart, Backscatter

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Proceedings Article | 5 June 2002 Paper

Paper

EMPHO-oxygradient II for monitoring in organs during surgery and gastrointestinal diseases

Manfred Kessler, Dumitru Nastac, Peter Koller

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469438

KEYWORDS: Capillaries, Surgery, Tissues, Heart, Tissue optics, Sensors, Oxygen, Spectroscopy, Endoscopes, Computing systems

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Proceedings Article | 5 June 2002 Paper

Paper

Imaging of dynamic alteration of functional structures

Manfred Kessler, Michael Singer, Markus Boehnert

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469462

KEYWORDS: Liver, Tissues, Tissue optics, Hypoxia, Near infrared, Switching, Oxygen, Dynamical systems, Optical sensors, Capillaries

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Proceedings Article | 5 June 2002 Paper

Paper

EMPHO-oxygradient I for monitoring in skin and skeletal muscle

Manfred Kessler, Peter Koller, Dumitru Nastac

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469437

KEYWORDS: Light scattering, Scattering, Tissue optics, Tissues, Heart, Skin, Optical sensors, Calibration, Computing systems, Near infrared

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Proceedings Article | 5 June 2002 Paper

Paper

Pig hearts from the abattoir: another approach to an isolated perfusion model

Tobias Trinks, Manfred Kessler, Michael Hiller, Robert Rauh

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.491250

KEYWORDS: Heart, Tissue optics, Oxygen, Animal model studies, Silicon, Physiology, Optical testing, Lung, Calcium, Cardiology

Proceedings Article | 5 June 2002 Paper

Paper

Imaging of interferences between cellular particles and the fluorescent dye Merocyanine-540 during normoxia and anoxia

Manfred Kessler, Marc Dammann, Valerie Steinbach, Maria-Theresa Stingl, Christine Mahlke

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469466

KEYWORDS: Liver, Luminescence, Tissues, Particles, Tissue optics, Hypoxia, Action potentials, Light scattering, Molecules, Physiology

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Proceedings Article | 5 June 2002 Paper

Paper

2D imaging of intracapillary Hb-concentration and oxygenation in the skin of the human forehead in different ages

Rainer Knaelmann, Paul Cristea, Manfred Kessler, Philipp Wittwer

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469446

KEYWORDS: Skin, Oxygen, Capillaries, Tissues, Visualization, Image fusion, Blood, Stochastic processes, Medical imaging, Data fusion

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Proceedings Article | 5 June 2002 Paper

Paper

Changes in quantitative oxygen uptake rate and redox state of cytochromes as a function of normal, critical, and anoxic conditions

Marc Dammann, Manfred Kessler, Klaus Frank, Valerie Steinbach

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469463

KEYWORDS: Oxygen, Tissues, Capillaries, Resistance, Heart, Light scattering, Scattering, Liver, Tissue optics, Waveguides

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Proceedings Article | 5 June 2002 Paper

Paper

What must be the accuracy and target of optical sensor systems for patient monitoring?

Manfred Kessler, Klaus Frank

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469457

KEYWORDS: Oxygen, Capillaries, Blood, Optical sensors, Tissue optics, Tissues, Heart, Spectroscopy, Hydrogen, Electrodes

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Proceedings Article | 5 June 2002 Paper

Paper

Hypokinesia of myocardium of perfused rat heart at different oxygenation of myoglobin and redox state of cytochrome

Klaus Frank, Manfred Kessler, D. Tauschek, J. Zuendorf

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469455

KEYWORDS: Heart, Oxygen, Capillaries, Acquisition tracking and pointing, Tissues, Tissue optics, Spectroscopy, Electrodes, Signal generators, Oxidation

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Proceedings Article | 5 June 2002 Paper

Paper

Quantitative monitoring of drug-tissue interaction in perfused organs

Klaus Frank, Manfred Kessler, Dumitru Nastac

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469468

KEYWORDS: Tissues, Liver, Capillaries, Mathematical modeling, Sensors, Medicine, Pharmacology, Optical sensors, In vitro testing, Image sensors

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Proceedings Article | 5 June 2002 Paper

Paper

Histograms obtained by local monitoring in patients: significance of arterial and venous intracapillary HbO2 and distribution of blood in supply units of tissue

Jens Hoeper, Manfred Kessler

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469441

KEYWORDS: Capillaries, Blood, Surgery, Heart, Tissues, Tissue optics, Arteries, Oxygen, Sodium, Sensors

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Proceedings Article | 5 June 2002 Paper

Paper

Arrangements of multiple images of human myocardium for information for the surgeon during open heart surgery

Michael Hiller, Manfred Kessler, Tobias Trinks, Paul Cristea

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469449

KEYWORDS: Surgery, Heart, Tissues, Information visualization, Optical sensors, Tissue optics, Hypoxia, Visualization, Acoustics, Signal detection

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Proceedings Article | 5 June 2002 Paper

Paper

Oxygen supply (HbO2) in beating hearts of 14 coronary patients obtained by tissue monitoring with optical sensors

P. Kloevekorn, J. Zuendorf, Klaus Frank, Manfred Kessler

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469452

KEYWORDS: Surgery, Oxygen, Heart, Capillaries, Arteries, Angiography, Tissue optics, Waveguides, Optical sensors, Diagnostics

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Proceedings Article | 5 June 2002 Paper

Paper

Detection of functional structures in isolated perfused pig heart: methods and technical principles

Michael Hiller, Tobias Trinks, Manfred Kessler, Robert Rauh

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469454

KEYWORDS: Waveguides, Heart, Tissue optics, Light scattering, Natural surfaces, Particles, Tissues, Scattering, Absorption, Chromophores

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Proceedings Article | 5 June 2002 Paper

Paper

Quantitative optical differences between 2D images of human myocardium and liver tissue

Tobias Trinks, Michael Hiller, Robert Rauh, Manfred Kessler, Michael Singer

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469451

KEYWORDS: Liver, Heart, Tissues, Tissue optics, Oxygen, Optical sensors, Capillaries, Blood, Acquisition tracking and pointing, Physiology

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Proceedings Article | 5 June 2002 Paper

Paper

Imaging of drug effects in perfused liver

Christine Mahlke, Marc Dammann, Manfred Kessler

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469470

KEYWORDS: Liver, Veins, Absorption, Oxygen, Optical fibers, Spectroscopy, Capillaries, Tissues, Physiology, Cardiology

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Proceedings Article | 5 June 2002 Paper

Paper

2D imaging of functional structures in perfused pig heart

Michael Hiller, Tobias Trinks, Paul Cristea, Manfred Kessler

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469448

KEYWORDS: Heart, Light scattering, Near infrared, Imaging systems, Visualization, Tissue optics, Oxygen, Physiology, Cardiology, Liver

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Proceedings Article | 5 June 2002 Paper

Paper

Multiple influence of Merocyanine-540 on spectra of perfused rat liver

Christine Mahlke, Marc Dammann, Manfred Kessler, Maria-Theresa Stingl

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469467

KEYWORDS: Liver, Tissues, Luminescence, Veins, Tissue optics, Light scattering, 3D image processing, Cell mechanics, Oxygen, Absorption

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Proceedings Article | 5 June 2002 Paper

Paper

Catchment volume and penetration depth in different suspensions of liver mitochondria monitored in scattering chambers

Manfred Kessler, Valerie Steinbach, Marc Dammann, Michael Singer, Christine Mahlke

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469440

KEYWORDS: Liver, Optical fibers, Scattering, Light scattering, Tissue optics, Particles, Absorption, Tissues, Veins, Spectroscopy

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Proceedings Article | 31 October 2001 Paper

Paper

Improvement of resolution in detection of 3D-functional structures in isolated perfused pig heart

Manfred Kessler, Michael Hiller, Tobias Trinks, Robert Rauh

Proceedings Volume 4432, (2001) https://doi.org/10.1117/12.447149

KEYWORDS: Heart, Waveguides, Tissue optics, 3D modeling, Light scattering, Physiology, Optical fibers, Cardiology, Spectroscopy, Tissues

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Proceedings Article | 31 October 2001 Paper

Paper

Separation of myoglobin and hemoglobin in isolated perfused pig heart

Michael Hiller, Manfred Kessler, Tobias Trinks, Robert Rauh

Proceedings Volume 4432, (2001) https://doi.org/10.1117/12.447147

KEYWORDS: Heart, Absorption, Tissue optics, Tissues, Blood, Physiology, Light scattering, Scattering, Cardiology, Visible radiation

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Proceedings Article | 10 May 2001 Paper

Paper

Precise separation of us and ua in tissue by use of 3D to 5D imaging

M. Singer, Manfred Kessler, Markus Boehnert, Andre Nicklas, Robert Rauh

Proceedings Volume 4260, (2001) https://doi.org/10.1117/12.426758

KEYWORDS: Tissues, Liver, Capillaries, Carbon dioxide, Tissue optics, Matrices, Heart, Absorption, Mathematical modeling, Visible radiation

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Proceedings Article | 4 May 2001 Paper

Paper

First spatial and high-resolution imaging in perfused pig heart: intracellular 3D monitoring of myoglobin, cytochromes, and subcellular structures of myocytes by use of EMPHO-Oxyscan

Robert Rauh, Christine Mahlke, Markus Boehnert, Manfred Kessler

Proceedings Volume 4241, (2001) https://doi.org/10.1117/12.431554

KEYWORDS: Heart, Particles, Light scattering, Tissue optics, Absorption, 3D modeling, 3D image processing, Hypoxia, Scattering, Tissues

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Proceedings Article | 4 May 2001 Paper

Paper

Spectral measurements of dc potentials in perfused rat liver by the use of Merocyanine-540

Markus Boehnert, Christine Mahlke, Manfred Kessler, Robert Rauh

Proceedings Volume 4241, (2001) https://doi.org/10.1117/12.431558

KEYWORDS: Liver, Luminescence, Tissues, Action potentials, Heart, Tissue optics, Axons, Optical testing, Temperature metrology, Molecules

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Proceedings Article | 4 May 2001 Paper

Paper

Simulation of basic subcellular scattering in tissues

Juergen Spaeth, Manfred Kessler, Martin Radina

Proceedings Volume 4241, (2001) https://doi.org/10.1117/12.431557

KEYWORDS: Scattering, Tissues, Light scattering, Particles, Absorption, Chemical elements, Waveguides, Multiple scattering, Computer simulations, Diffusion

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Proceedings Article | 4 May 2001 Paper

Paper

Effect of inspiratory oxygen fraction and perfusion pressure on 3D functional structures during hypoxia and reoxygenation in isolated perfused pig heart

Robert Rauh, Markus Boehnert, Manfred Kessler

Proceedings Volume 4241, (2001) https://doi.org/10.1117/12.431546

KEYWORDS: Heart, Light scattering, Hypoxia, Tissue optics, Oxygen, 3D modeling, Particles, Capillaries, Surgery, Tissues

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Proceedings Article | 4 May 2001 Paper

Paper

Spatial imaging of cooperative systems in capillaries (Hb, HbO2) and cells (Redox states and changes of subcellular functional structures) in perfused liver

Robert Rauh, Markus Boehnert, Manfred Kessler

Proceedings Volume 4241, (2001) https://doi.org/10.1117/12.431569

KEYWORDS: Liver, Tissues, Light scattering, Near infrared, Imaging systems, Veins, Visible radiation, Particles, Capillaries, Optical testing

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Proceedings Article | 3 November 2000 Paper

Paper

Optical investigation of functional structures in isolated perfused pig heart

Christine Mahlke, Robert Rauh, Manfred Kessler, Markus Boehnert

Proceedings Volume 4162, (2000) https://doi.org/10.1117/12.405944

KEYWORDS: Heart, Tissue optics, Light scattering, Particles, Absorption, 3D modeling, Scattering, Tissues, Hypoxia, Animal model studies

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Proceedings Article | 6 April 2000 Paper

Paper

Comparative remission-spectrophotometric investigations in skin with EMPHO SSK

Rainer Knaelmann, Philipp Wittwer, Paul Cristea, Manfred Kessler

Proceedings Volume 4001, (2000) https://doi.org/10.1117/12.381530

KEYWORDS: Capillaries, Skin, Tissues, Oxygen, Tissue optics, Diffusion, Physiology, Liver, Blood circulation, Waveguides

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Proceedings Article | 6 April 2000 Paper

Paper

Controlled therapy by imaging of functional structures of intact liver

Feng Zhuang, G. Ruan, W. Wang, Yasuyuki Kakihana, Manfred Kessler, A. Krug

Proceedings Volume 4001, (2000) https://doi.org/10.1117/12.381516

KEYWORDS: Liver, Tissues, Capillaries, Oxygen, Medicine, Blood, Veins, Sensors, Blood circulation, Stereoscopy

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Proceedings Article | 18 August 1997 Paper

Paper

Noninvasive investigation of skin local hypothermia influence upon local oxygenation and hemoglobin concentration

Manfred Kessler, Yasuyuki Kakihana, Alfons Krug, Alexandre Douplik

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280267

KEYWORDS: Skin, Photodynamic therapy, Tissue optics, Blood, Laser tissue interaction, In vivo imaging, Spectroscopy, Tissues, Scattering, Visible radiation

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Proceedings Article | 18 August 1997 Paper

Paper

Model validation and improved determination of chromophore concentrations in quantitative tissue spectrophotometry

Alfons Krug, Sabine Van Huffel, Manfred Kessler

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280295

KEYWORDS: Liver, Principal component analysis, Chromophores, Tissue optics, Tissues, Optical testing, Spectrophotometry, Data modeling, Canonical correlation analysis, Absorption

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Proceedings Article | 18 August 1997 Paper

Paper

Validation and improvements of an algorithm for the determination of hemoglobin oxygenations based on spectral data recorded by a tissue spectrophotometer

Alfons Krug, Manfred Kessler

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280263

KEYWORDS: Scattering, Light scattering, Tissue optics, Oxygen, Tissues, Absorption, Capillaries, Scattering media, Modulation, Visible radiation

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Proceedings Article | 18 August 1997 Paper

Paper

Stable and reliable measurement of intracapillary hemoglobin-oxygenation in human skin by EMPHO II

Alfons Krug, Manfred Kessler, Yasuyuki Kakihana, Alexandre Douplik

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280268

KEYWORDS: Skin, Oxygen, Ischemia, Tissues, Blood circulation, Temperature metrology, Reliability, Sensors, Spectrophotometry, Hypoxia

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Proceedings Article | 11 December 1996 Paper

Paper

Investigation of local heterogeneity of hbO2 and hb in working dog heart in situ under isovolemic hemodilution and critical coronary stenosis

Robert Lust, Manfred Kessler, Randolph Chitwood, Alfons Krug, Raja Khuri

Proceedings Volume 2927, (1996) https://doi.org/10.1117/12.260636

KEYWORDS: Capillaries, Tissues, Oxygen, Hypoxia, Heart, Waveguides, Blood, Hyperoxia, Tissue optics, Sensors

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Proceedings Article | 6 December 1996 Paper

Paper

Functional images of local O2 contents and O2 gradients in intact human skin

Manfred Kessler, Jens Hoeper, Alfons Krug, Paul Cristea, Barbara Albert-Hehn

Proceedings Volume 2926, (1996) https://doi.org/10.1117/12.260823

KEYWORDS: Skin, Oxygen, Capillaries, Tissues, Image processing, Visualization, Fourier transforms, Tissue optics, Spectroscopy, Optical testing

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Proceedings Article | 5 April 1996 Paper

Paper

Noninvasive topographical investigation of functional parameters in the human skin

Jens Hoeper, Manfred Kessler, Alfons Krug

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237591

KEYWORDS: Skin, Capillaries, Oxygen, Blood, Spectroscopy, Waveguides, Sensors, Tissue optics, Calibration, Rubidium

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Proceedings Article | 12 April 1995 Paper

Paper

Analysis of downregulation of cellular energy demand by 2D measurements of intracapillary HbO2, Hb, pO2, and redox state of cytochromes

Manfred Kessler, S. Zellner, Alfons Krug, Jens Hoeper, Valerie Sourdoulaud

Proceedings Volume 2387, (1995) https://doi.org/10.1117/12.206830

KEYWORDS: Tissues, Liver, Heart, Tissue optics, Oxygen, Capillaries, Electrodes, Sensors, Near infrared, Blood

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Proceedings Article | 31 January 1995 Paper

Paper

Intensity of intracapillary hemoglobin remission spectra as a function of hemoglobin concentration

Alfons Krug, Manfred Kessler, M. Batz, S. Aigner, Juergen Spaeth

Proceedings Volume 2326, (1995) https://doi.org/10.1117/12.200832

KEYWORDS: Light scattering, Scattering, Tissue optics, Tissues, Absorption, Spectroscopy, Particles, Electromagnetic scattering, Heart, Mirrors

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Proceedings Article | 4 January 1995 Paper

Paper

Simultaneous monitoring of NAD(P)H, cytochromes, pO2, and HbO2 in liver tissue

Manfred Kessler, M. Batz, Jens Hoeper, Andreas Otto, D. Gaertner, Alfons Krug, S. Zellner

Proceedings Volume 2324, (1995) https://doi.org/10.1117/12.198715

KEYWORDS: Tissues, Liver, Luminescence, Oxygen, Visible radiation, Near infrared, Waveguides, Tissue optics, Lamps, Natural surfaces

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Proceedings Article | 1 February 1994 Paper

Paper

Physiological reactions of the denture-bearing mucosa following mechanical stress

F. Gutmann, Manfred Kessler, Wilhelm Niedermeier, K. Frank

Proceedings Volume 2084, (1994) https://doi.org/10.1117/12.167303

KEYWORDS: Tissues, Blood, Oxygen, Physiology, Injuries, Spectrophotometry, Ischemia, Dentistry, Medicine, Hypoxia

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Proceedings Article | 14 September 1993 Paper

Paper

Multiple multipole scattering of light in mitochondrial suspensions

Klaus Frank, Martin Radina, Manfred Kessler

Proceedings Volume 1888, (1993) https://doi.org/10.1117/12.154645

KEYWORDS: Light scattering, Particles, Scattering, Mie scattering, Tissues, Multiple scattering, Liver, Energy transfer, Tissue optics, Heart

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Proceedings Article | 1 May 1991 Paper

Paper

Analysis of multiple-multipole scattering by time-resolved spectroscopy and spectrometry

Jochen Wiesner, Klaus Frank, Jens Hoeper, Alexander Wokaun, Manfred Kessler, J. Zuendorf, D. Tauschek

Proceedings Volume 1431, (1991) https://doi.org/10.1117/12.44172

KEYWORDS: Scattering, Light scattering, Particles, Time resolved spectroscopy, Tissues, Imaging spectroscopy, Tissue optics, Multiple scattering, Picosecond phenomena, Liver

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Showing 5 of 49 publications

Proceedings Volume Editor (1)

SPIE Conference Volume | 5 June 2002

Functional Monitoring and Drug-Tissue Interaction

Conference Committee Involvement (4)

Microarrays, Combinatorial Techniques and High Throughput Screening

25 January 2004 | San Jose, CA, United States

Manipulation and Analysis of Biomolecules, Cells and Tissues

28 January 2003 | San Jose, CA, United States

Microarrays and Combinatorial Technologies for Biomedical Applications: Design, Fabrication, and Analysis

26 January 2003 | San Jose, CA, United States

Functional Monitoring and Drug-Tissue Interaction

21 January 2002 | San Jose, CA, United States

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